Vijayalakshmi, B (2007) Morphoea - A Clinical study. Masters thesis, Madras Medical College, Chennai.
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Abstract
INTRODUCTION : Morphoea is a benign disorder characterized by localized thickening of the skin with no known aetiological factors. Although the skin disorder resembles systemic scleroderma there are no internal organ involvement. Morphoea is more commonly found in females and it has a characteristic morphology which differs in early and late stage. There are varying clinical types. All have characteristic distribution across the age groups. Morphoea may cause a lot of cosmetic problems which is very distressing to the patients. Sometimes it may cause growth retardations, deformity, contractures and disfigurement. There have been rare occurrence of pain, oedema, arthritis, colicky abdominal pain, visual disturbances and neurological problems in patients of morphoea. There are also interesting serological associations in morphoea. The interesting fact about morphoea is that it resolves on its own even without treatment. So far no conclusive evidence regarding its etiopathogenisis has been proposed in spite of the advancements in the field of medicine and technology. This disease, with such peculiar manifestations has kindled the interest of dermatologist from time immemorial. Several eminent dermatologists have contributed to the knowledge of morphoea. AIMS OF THE STUDY : 1 To study the incidence of Morphoea in Government General Hospital, Chennai during the period of two years between September 2004 and September 2006 2. To study the incidence of various types of Morphoea. 3. To study the sex wise distribution. 4. To study the age wise distribution. 5. To study the commonest site of lesions. 6. To study the main presenting complaints. 7. To study the precipitating factors. 8. To study the relevant serological abnormalities. 9. To study the associated autoimmune disorders. 10. To study the other associated anomalies. 11. To correlate the Histopathological findings with various types of morphoea. 12. To study the incidence of morphoea in relatives. CONCLUSION : * The incidence of Morphoea in Government General Hospital during the period of September 2004 to September 2006 was 1 in 1000. * The incidence of various types of Morphoea were as follows PLAQUE TYPE 34% LINEAR TYPE 36% GENERALIZED TYPE 5% MIXED TYPE 5% FRONTOPARIETAL TYPE 20% * The female to male sex ratio was 2:1. * The maximum number of patients were in the age groups of 10 to 25years of age. * Linear morphoea was more commonly seen in lower limbs. * The main complaints of patients was disfigurement. * One of the precipitating factors was found to be trauma. * Serological investigations showed eosinophilia in 66% of patients. * ESR was raised in 41% of patients.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Morphoea ; Clinical study. |
| Subjects: | MEDICAL > Dermatology Venereology and Leprosy |
| Depositing User: | Subramani R |
| Date Deposited: | 05 Jul 2017 02:06 |
| Last Modified: | 05 Jul 2017 08:28 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/946 |
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