Ravi, P (2015) Impact of Intravenous Lignocaine on Intraoperative Haemodynamics, Recovery Characteristics, Post-OP Pain Scores, Post OP Analgesic Requirement & Return of Bowel Function in Patients Undergoing Laproscopic Cholecystectomy. Masters thesis, Madurai Medical College, Madurai.
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Abstract
BACKGROUND: Post-operative pain after laproscopic cholecystectomy procedures are being rated from mild to severe in the literature. Post operative pain Most of the patients suffer from miled to severe pain after laparoscopic cholecystectomy. Different modalities for adequate control of pain management in these scenario are described including opioids, NSAIDs, local anesthetic infiltration of port site and local anesthesia infusion through epidural route, but none of them are proven to be consistently satisfactory. AIMS AND OBJECTIVES: To study the impact of intravenous Lignocaine on intra-operative Haemodynamics, recovery characteristics, post-op pain scores, post-op analgesic requirement and return of bowel function in patients undergoing Laproscopic Cholecystectomy. METHODOLOGY: After obtaining necessary approval from Institutional ethical committee, this prospective randomized single blinded case control study was started. The study was conducted in Institute of Anesthesiology, Govt. Rajaji Hospital, Madurai. The study subjects were selected from patients posted for Laparoscopic Cholecystectomy. The inclusion criteria were : 1. American Society of Anesthesiology (ASA) Grading 1 & 2, 2. Age > 18 years, 3. Both Gender. The exclusion criteria were : 1. ASA 3, 4, 2. H/o Allergy to Lidocaine, 3. H/o Anti-arrhythmic Drugs, 4. H/o Drug abuse, 5. H/o Chornic Alcoholism, 6. H/o Cardiac Diseases, 7. H/o Bleeding Disorder, 8. H/o Liver Disease Patient Refusal. After assessing Inclusion & Exclusion criteria 60 patients were selected. Informed consent was obtained from patients who were willing to participate in the study. On the day of surgery, patients were shifted to operating room. Intravenous access was obtained with 18 gauge Cannula. Electro- cardiogram (ECG), Non-Invasive Blood Pressure (NIBP) and Pulse Oximeter were attached and baseline heart rate, saturation of Hemoglobin (SpO2) and blood pressure were recorded. SUMMARY: In this study, we evaluate the impact of intravenous Lignocaine on Intraoperative haemodynamics, recovery characteristics, post of pain scores,post op analgesic requirement & Return of bowel function in patients undergoing laproscopic cholecystectomy. Sixty patients of ASA 1&2 of either sex divided into two groups, thirty patients in each group. Group L – Lidocaine Group, Group S - Saline Group. The study was done at Govt. Rajaji Hospital and Madurai Medical College between the period of 3 years. In our study, group the Age of the patients, Sex distribution and weight are not statistically significant. There is stable introperative hamodynamics, heart rate, mean blood pressure in lidocaine group. There is lower post operative pain score in lidocaine group. Early bowel movements in lidocaine group. CONCLUSION: Lidocaine Infusion started (1.5mg/Kg) before induction and continued (1.5mg/Kg/Hr) for one hour intra-operatively results in intra- op hamodynamic stability, lesser post operative pain, lesser use of rescue analgesics and early return of bowel function compared to placebo.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Impact of Intravenous Lignocaine ; Intraoperative Haemodynamics ; Recovery Characteristics ; Post-OP Pain Scores ; Post OP Analgesic Requirement ; Return of Bowel Function ; Patients ; Undergoing Laproscopic Cholecystectomy. |
| Subjects: | MEDICAL > Anaesthesiology |
| Depositing User: | Punitha K |
| Date Deposited: | 07 May 2018 04:15 |
| Last Modified: | 08 May 2018 10:01 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/7581 |
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