Jawahar, S (2006) hs-C-Reactive Protein in Chronic Renal Failure With and Without Cardiovascular Complications. Masters thesis, Madurai Medical College, Madurai.
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Abstract
In the present study a group of 42 newly detected CRF patients (28 males and 14 females) were selected and 10 normal individuals (5 males and 5 females) were selected as control group after careful application of inclusion and exclusion criteria. They were subjected to detailed sociodemographic clinical and systemic examination and routine laboratory tests. The study subjects underwent ultrasonographic evaluation. A single time fasting blood sample was obtained and hs-CRP assay was done. Then they underwent funduscopic and echocardiographic evaluation. The results obtained were statistically analysed using Epi info-2002. CRF patients are susceptible to cardiovascular morbidity and mortality. Various risk factors have been identified in them. One another risk factors was elevated hsCRP the present study has made an attempt to find out hsCRP levels in the selected CRF patients and correlate the levels with albuminuria, haemoglobin levels, severity of retinopathy and cardiovascular complications. The hsCRP levels were significantly elevated in the CRF patients (Mean 1.22mg% SD ± 0.99mg%) than the control (Mean 0.08mg% SD ± 0.01mg%) and it was independent of age, gender and serum creatinine levels. However elevated hsCRP correlated with albuminuria, haemoglobin levels, severity of retinopathy and cardiovascular morbidity. The hsCRP measurement may well prove an exception in view of its robustness, its relative stability in individuals over time, and most importantly its ability to add to the cardiovascular risk information. Areas for future research and recommendation were identified.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | hs-C-Reactive Protein ; Chronic Renal Failure ; With and Without Cardiovascular Complications. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 15 Mar 2018 02:28 |
| Last Modified: | 15 Mar 2018 02:28 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/6212 |
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