Arun Prasad, R (2011) The Remineralization Potential of CPP-ACP (GC Tooth Mousse) and TCP with 0.21% W/W Sodium Fluoride Anti-Cavity Paste (Clinpro Tooth Crème) on Artificial Caries – Like Subsurface Lesions in Primary and Permanent Teeth : An In Vitro study. Masters thesis, Ragas Dental College and Hospital, Chennai.
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Abstract
This In-vitro study was designed to investigate the effect of CPP-ACP (GC tooth mousse) and TCP with 0.21% w/w sodium fluoride anti-cavity paste (clinpro tooth crème) on remineralization of artificial caries – like subsurface lesions in primary and permanent teeth. Twenty human permanent and twenty primary teeth were collected. All the teeth were coated with an acid resistant nail varnish (Revlon, USA) leaving two narrow rectangular windows (occlusal 1/3 and gingival 1/3) of approximately 1mm size, on the intact buccal surface. Then immersed in demineralizing solution for 96 hrs to create artificial sub-surface caries lesions. The samples from permanent teeth (n=20) were then randomly assigned to two Groups I and II and primary teeth (n=20) were then randomly assigned to two Groups III and IV based on the treatment agents applied. GROUP I - CPP-ACP (GC Tooth mousse) in permanent teeth, GROUP II - TCP with 0.21%w/w sodium fluoride (CLINPRO) in Permanent teeth, GROUP III- CPP-ACP (GC Tooth mousse) in Primary teeth, GROUP IV- TCP with 0.21%w/w sodium fluoride (CLINPRO) in Primary teeth Topical application of the remineralizing agents (GC Tooth Mousse and Clinpro) was carried out for three minutes twice daily followed by immersing in remineralizing solution for 10 days in permanent teeth and 7 days in primary teeth. The solution concentration and pH were maintained in the range reported to exist in oral fluids. To avoid the risk of solutions becoming saturated, fresh remineralizing solutions were changed daily. After the treatment period, the mineral content was quantified using EDAX & surface morphology was analyzed under SEM. The values were statistically analyzed. The effect of remineralizing agents was evaluated from the EDAX Calcium and Phosphorous values. They were converted into Ca/P ratio of study groups and are represented in Table [I - IV] Remineralization effect of two pastes were compared and shown in Table [VI]. On Comparison of Ca/P Ratios CPP-ACP (Group I) 0.105 ± 0.0512 showed better remineralizing efficacy than TCP with 0.21% w/w Sodium Fluoride (Group II) 0.088 ± 0.0330 in Permanent teeth, which was not statistically significant (P=0.389). On Comparison of Ca/P Ratios CPP-ACP (Group III) 0.214± 0.0232 showed better remineralizing effect than TCP with 0.21% w/w Sodium Fluoride (Group IV) 0.170± 0.0290 in Primary teeth which was statistically significant. (P=0.001). Both CPP-ACP (GC TOOTH MOUSSE) and TCP with 0.21% w/w Sodium Fluoride (CLINPRO) showed remineralization capacity, with CPPACP showing better remineralization capacity when compared to TCP with significant effect in primary teeth.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Remineralization Potential, CPP-ACP, GC Tooth Mousse, TCP , 0.21% W/W Sodium Fluoride Anti-Cavity Paste Clinpro Tooth Creme, Artificial Caries, Subsurface Lesions, Primary and Permanent Teeth. |
| Subjects: | DENTAL > Paedodontics and Preventive Dentistry |
| Depositing User: | Kambaraman B |
| Date Deposited: | 22 Jan 2018 12:03 |
| Last Modified: | 22 Jan 2018 12:03 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/5524 |
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