Subha, J (2016) Virological characterization of BK virus among HIV-1 infected individuals and its association with immunosuppression. Masters thesis, Christian Medical College, Vellore.
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Abstract
The human Polyomavirus BK virus (BKV) is an opportunistic pathogen which causes significant morbidity and mortality in immunocompromised population. As HIV causes significant immunosuppression, it is important to determine the frequency and viral load of BK virus which are usually increased in these individuals. The frequency of BK viruria in HIV-1 infected individuals is higher than healthy controls. There is a strong association of BKV viruria with the extent of immunosuppression. The frequency and viral load of BKV among HIV infected individuals is very low unlike in transplant settings. NCCR rearrangements were not associated with high BK viral load in urine or clinically severe disease.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | BK virus ; HIV ; Immunosuppression ; Genotype. |
| Subjects: | MEDICAL > Microbiology |
| Depositing User: | Punitha K |
| Date Deposited: | 23 Jun 2017 06:50 |
| Last Modified: | 09 Dec 2018 04:02 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/329 |
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