Hepatoprotective Activity of Siringipaerathi Chooranam on Ccl4 and Paracetamol Induced Hepatotoxicity and Anti - Oxidant Activity in In-Vivo and In-Vitro Models.

Vijayanirmala, R (2016) Hepatoprotective Activity of Siringipaerathi Chooranam on Ccl4 and Paracetamol Induced Hepatotoxicity and Anti - Oxidant Activity in In-Vivo and In-Vitro Models. Masters thesis, Government Siddha Medical College, Chennai.

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Abstract

The study and the treatment of liver diseases, but there is a need for the drug which could be less toxic, cost effective and more potent. Among them, one of the polyherbal formulation mentioned in Siddha literature for hepatoprotective activity is “Siringipaerathi Chooranam” consists of Piper longum, Cuminum cyminum, Syzygium aromaticum, Bambusa arundinacea and Cinnamomum tamala which acts as a Hepatoprotective and Antioxidant activities, The test drug Siringipaerathi Chooranam was selected from the Siddha literature SARABENDRA VAIDHYA MURAIGAL for its hepatoprotective activity. The dissertation started with an introduction explaining about the Siddha concept, prevalence of jaundice and role of the test drug in treating hepatic diseases. The review of literature strengthened the positive facts of possessing the hepatoprotective activity by each of the single drug included in the formulation. The pharmacological review possessed all the information regarding the exertion of action of the drugs, available drugs in the market, their adverse effects,Pharmacological study was done. It revealed the hepatoprotective and antioxidant activity of Siringipaerathi Chooranam in animal model Wistar albino rats and In-vitro studies, the study and explains the synergistics and activities that supports the study.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Hepatoprotective Activity; Siringipaerathi Chooranam; Paracetamol; Hepatotoxicity; Anti Oxidant Activity
Subjects: AYUSH > Gunapadam
Depositing User: Ravindran C
Date Deposited: 03 Aug 2017 06:36
Last Modified: 03 Aug 2017 06:36
URI: http://repository-tnmgrmu.ac.in/id/eprint/2480

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