RP-HPLC Method Development and Validation for Estimation of Isoniazid and Rifampicin in Tablet Dosage Form.

Yelle, Sudheer Kumar (2014) RP-HPLC Method Development and Validation for Estimation of Isoniazid and Rifampicin in Tablet Dosage Form. Masters thesis, K M College of Pharmacy, Madurai, Tamil Nadu, India..

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Abstract

The pharmaceutical analysis defined as “the branch of practical chemistry which deals with the resolution, separation, identification, determination and purification of a given sample of a medicine, the detection and estimation of impurities, which may be present in drug substance (or) given sample of medicine”. The substance may be a single compound or a mixture of compounds and may be in the form a tablet, pill, capsule, ampoule, liquid, mixture or an ointment. The quality control tests involve methods which embrace chemicals, physio – chemical, instrumental, microbiological (or) biological procedures. The present study observed that the developed method was proven to be specific, precise, linear, accurate, rugged and robust and is suitable for its intended purpose. So the above work performed gives documented evidence that the analytical method for the Isoniazid and Rifampicin by RP-HPLC in tablet dosage forms will consistently analyze these drugs quantitatively and could be used for routine analysis.

Item Type: Thesis (Masters)
Uncontrolled Keywords: RP- HPLC Method; Isoniazid; Rifampicin; Tablet Dosage Form
Subjects: PHARMACY > Pharmaceutical Analysis
Depositing User: Ravindran C
Date Deposited: 27 Jul 2017 09:47
Last Modified: 28 Jul 2017 06:32
URI: http://repository-tnmgrmu.ac.in/id/eprint/2278

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