Kanneganti Venkata Naga Gopal, T I (2022) A Cross Sectional study on Rhino-Orbital Mucormycosis in Post COVID Patients during COVID Pandemic in a Tertiary Hospital. Masters thesis, Madras Medical College, Chennai.
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Abstract
INTRODUCTION: Covid-19 or Corona virus disease 2019 is a new disease which is caused due to infection with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It began in Wuhan, China in December 2019, later spreading rapidly throughout the world. World Health Organization declared it to be a pandemic on March 11, 2020. India reported its first case of Covid-19 on 30th January, 2020 in Kerala. As of December 2021, a total of 278,891,403 cases and 5,392,790 deaths were reported in the world and in India reporting 34 765 976 cases and 478 759 deaths due to Covid-19. JUSTIFICATION: a. Identification of incidence, clinical profile of rhinoorbital Mucormycosis in post covid patients will provide useful knowledge for the prevention, early identification, treatment and reduction of morbidity and mortality. b. I chose this study due to paucity of studies related to rhino-orbital Mucormycosis in post covid patients in Tamilnadu. OBJECTIVES: 1. To study the incidence of Rhino orbital Mucormycosis in post covid patients. 2. To analyse the clinical profile of rhino orbital Mucormycosis in post covid patients. 3. To study the risk factors and Immunisation status among the post covid patients developing Mucormycosis. 4. Role of mycology, Histopathology and radiology in the diagnosis of Rhino-orbito-cerebral Mucormycosis. 5. To develop a diagnostic-criteria for Mucormycosis based on clinical profile and Investigations. METHODOLOGY: STUDY DESIGN: This study is a hospital based Cross sectional study conducted in RGGGH, MMC, Chennai. STUDY POPULATION: Patient who admitted in Mucor ward in RGGGH, Chennai. STUDY DURATION: MAY 2021 TO SEPTEMBER 2021 (6 months period). STUDY AREA: Rajiv Gandhi Government General Hospital, Chennai - 600 003. INCLUSION CRITERIA: Post covid patients with new onset rhinoorbital mucormycosis Those who are willing to give informed consent. EXCLUSION CRITERIA: Patients with pre-existing rhino-orbital mucormycosis Those who are not willing to give consent. DATA COLLECTION TOOL: To collect A detailed clinical history, microbiological and radiological investigations in post covid patients with rhino-orbital mucormycosis. SAMPLING METHOD: Convenient sampling. CONCLUSION: ➢ Covid Associated Mucormycosis is more common in males and in the fifth decade. ➢ The most common risk factors associated with Mucormycosis in our study are post Covid status, Diabetes Mellitus, hospitalization and steroid administration. ➢ This epidemic within a pandemic stresses the fact that vaccine against Covid-19 is an indispensable tool in fighting the pandemic & its associated afflictions and highlights the burning need for 100% vaccination against Covid-19. ➢ Covid Associated Mucormycosis was not associated with steam inhalation, industrial oxygen or zinc supplementation. ➢ The predominant symptoms seen in Covid associated Mucormycosis were discerned to be nasal obstruction, nasal discharge, facial swelling and facial pain. ➢ The earliest sign of orbital involvement is abduction restriction. ➢ Our study accentuates the ability of CT paranasal sinuses with orbital cuts in identifying early subtle fat stranding in extra sinus tissues and highlights the diagnostic value of CT in recognizing Mucormycosis at an early stage. Though MRI is preferred and is better at picking up soft tissue changes, CT should be favoured due to its limited cost and easy accessibility with MRI being reserved for cases suspected to have advanced stage disease to promptly identify the same. ➢ Direct microscopy is a better screening tool for early diagnosis and initiation of treatment in Covid Associated Mucormycosis. LIMITATIONS: 1. our study was hospital based, not a community-based study. 2. The possibility of recall bias among the study population while data collection. 3. With many patients having treated for Covid elsewhere, the proper details regarding the Covid management couldn’t be collected satisfactorily.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221914013 |
| Uncontrolled Keywords: | hino-Orbital Mucormycosis, Post COVID Patients, COVID Pandemic, Tertiary Hospital. |
| Subjects: | MEDICAL > Otolaryngology > MEDICAL > Otolaryngology |
| Depositing User: | Subramani R |
| Date Deposited: | 22 Apr 2022 14:32 |
| Last Modified: | 17 Dec 2023 06:05 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/19370 |
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