Prabhavathi, K (2020) Formulation and Optimization of Topical Dapsone Nanoemulsion Gel for Acne Vulgaris. Masters thesis, Swamy Vivekanandha College of Pharmacy, Tiruchengode.
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Abstract
In this work, it was found that it is possible to incorporate dapsone into nanoemulsion systems containing excipients that are compatible with skin. The physicochemical characterization performed here demonstrates that the mean droplet size was in the nanometer range, with good uniformity of diameter and a pH suitable for topical formulation. The use of different oil phases in the nanoemulsion systems enabled evaluation of the differential performance of the systems with regard to in-vitro release and permeation of dapsone, with potential for pharmaceutical application. Thus, the present study demonstrated nanoemulsion gel of dapsone as a possible alternative to a conventional topical formulation for the treatment of acne vulgaris.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 261810601 |
| Uncontrolled Keywords: | Formulation, Optimization, Topical Dapsone Nanoemulsion Gel, Acne Vulgaris |
| Subjects: | PHARMACY > Pharmaceutics |
| Depositing User: | Ramakrishnan J |
| Date Deposited: | 21 Apr 2022 08:53 |
| Last Modified: | 21 Apr 2022 08:53 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/19356 |
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