Jancy Gracelet, R (2014) Drug Discovery Approach on Tectona Grandis Linn Leaves Against Apicomplexan Plasmodium and Wound Links its Ethnopharmacological Validation and Pharmacognostical Relevance. Masters thesis, College of Pharmacy, Madurai Medical College, Madurai, Tamil Nadu, India..
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Abstract
The plant constituents used for these latter purposes are largely secondary metabolites (like alkaloids,flavonoids,glycosides etc.) which are derived biosynthetically from plant primary metabolites (e.g carbohydrates, aminoacids and lipids) and are not directly involved in the growth, development or reproduction of plants. Arrow and dart poisons have been used in certain parts of the world with the principal ingredients derived from the genera Aconitum, Antiaris, Strophanthus, Strychnos etc. In some cultures some plants well documented for murder were henbane, mandrake, deadly nightshade, calabar bean etc. Certain plants formerly used for arrow poisons have also been used as medicines at lower dosages due to their desirable pharmacological actions the pharmacognostical, phytochemical and potential,(a new hope in the fight against apicomplexanPlasmodiumfalciparum) more effective antimalarial therapeutically comparable to the synthetic counterpart, without toxicity of the ethyl acetate extract of the leaves of TectonagranidisLinn family Verbenaceae, a widely, easily available plant commonly called as Teak plant. Ethno medical information revealed that it was used in various ailments for long time all over the world. It is traditionally known to be useful for the treatment of wide panel of diseases like tuberculosis, various kinds of wounds especially burn wound, malaria, anaemia, leprosy, skin diseases like pruritis, stomatitis, indolent ulcers, haemorrhages, menstrual disorder, bone joint disease. Young leaves and fruits prescribed to women for fertility control and fumes of dry leaves to kill guinea worms. It also possesses anti- ulcer and anti- cancer activity. Various scientific investigations of the leaves showed anti-diabetic activity, anti-microbial activity, anti-oxidant, analgesic, anti-inflammatory, anti-amoebic, anti-hypertensive and wound healing activity.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Drug Discovery; Tectona Grandis; Linn Leaves; Apicomplexan; Plasmodium; Ethnopharmacological; Validation; Pharmacognostical Relevance |
| Subjects: | PHARMACY > Pharmacognosy |
| Depositing User: | Ravindran C |
| Date Deposited: | 19 Jul 2017 08:50 |
| Last Modified: | 19 Jul 2017 08:50 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1897 |
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