Symptom Triggered Therapy for Alcohol withdrawal Symptoms using Revised Clinical Institute withdrawal Assessment of Alcohol Scale (CIWA-Ar) – A Randomized control study.

Sushith Sugathan, Chennatte (2012) Symptom Triggered Therapy for Alcohol withdrawal Symptoms using Revised Clinical Institute withdrawal Assessment of Alcohol Scale (CIWA-Ar) – A Randomized control study. Masters thesis, PSG Medical College, Coimbatore.

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Abstract

BACKGROUND : Alcohol related withdrawal symptoms are common problems encountered in alcohol dependent patients. Withdrawal symptoms exist in a continuum and there is need for timely treatment of these withdrawal symptoms in order to prevent complicated withdrawal states like Delirium tremens and withdrawal seizures. The treatment is by administration of benzodiazepines and the usual practice is to start patients on an empirical dose, “Fixed schedule treatment”. But there is another method called the “Symptom triggered treatment” for administering benzodiazepines which utilizes a rating scale called the Clinical Institute Withdrawal Assessment Scale (CIWA-Ar), which helps in giving medications according to severity of the withdrawal rating. AIMS OF THE STUDY : To compare between the two regimens for alcohol detoxification namely, the “Symptom triggered treatment” and the “Fixed schedule treatment” for outcome variables: Dose of benzodiazepine, duration of treatment and severity of withdrawal. METHODS : Prospectively we randomized consenting, consecutive patients, admitted with the diagnosis of alcohol dependence syndrome according to DSM-IV criteria into either of the 2 detoxification treatment methods: 1)Fixed schedule treatment or 2)Symptom triggered treatment. RESULTS : The “Symptom triggered treatment” group required 93 mg lesser mean benzodiazepine dose than the “Fixed schedule treatment” group. The mean duration of treatment in the “Symptom triggered treatment” was 2.12 days lesser than the “Fixed schedule treatment.” There was a group of patients who did not require any benzodiazepine during detoxification and they were significantly higher in the “Symptom triggered treatment” group (24%) when compared with the “Fixed schedule treatment” group (4%). No incidences of any complicated withdrawal symptoms during course of detoxification in the sample. CONCLUSION : The Symptom triggered treatment using CIWA-Ar scale may be a safe and better treatment option for patients during alcohol detoxification in terms of lower benzodiazepine dose and shorter duration of treatment.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Symptom Triggered Therapy ; Alcohol withdrawal ; Symptoms using ; Clinical Institute Withdrawal Assessment of Alcohol scale (CIWA-Ar) ; Randomized Control Study.
Subjects: MEDICAL > Psychiatry
Depositing User: Subramani R
Date Deposited: 16 Aug 2017 00:52
Last Modified: 16 Aug 2017 11:28
URI: http://repository-tnmgrmu.ac.in/id/eprint/1873

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