Manikandan, G (2023) Study of Thyroid Dysfunction in Type 2 Diabetes Mellitus. Masters thesis, Tagore Medical College & Hospital, Chennai.
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Abstract
BACKGROUND: Diabetes Mellitus (DM) is the most common metabolic disease characterized by features of hyperglycemia and metabolic disturbances caused due to pancreatic beta -cell zysfunction, increased renal glucose reabsorption and hyperglucagonemia. Conversely, DM could variably affect thyroid function. For example, the effect of TSH to thyrotropin- releasing hormone have been shown to be impaired in DM, leading to the hypothyroidism and concomitant lower T3 values. OBJECTIVE: Primary objective of the study is to measure the thyroid profile level in type 2 diabetics individuals and to compare the level of thyroid profile in type 2 diabetic individual and non -diabetic individuals with euthyroid. METHODOLOGY: Samples will be collected from patients presented with thyroid dysfunction in type 2 diabetes. Blood samples collected will be investigated for glycemic, lipid and thyroid profile. The data will analysed by SPSS software RESULTS: Thyroid dysfunction was detected in 43.3% among 150 type2 DM patients studied, out of which 22.7% was found to be hypothyroidism,5.3% of hyper thyroidism,12% of subclinical hypothyroidism and 3.3% of subclinical hyper thyroidism. Hyperthyroidism was more in prevalent in elderly type 2 DM patients and among males. But hypothyroidism was more prevalent among type 2DM female patients and among middle age group patients. CONCLUSION: The present study shows that DM have a higher prevalence of thyroid disorders than the normal population. Thyroid disease is found in both types 1 and 2 diabetes. Studies have found that thyroid dysfunction is much common in diabetic population compared to non-diabetic population, diabetes and thyroid disorders have been shown to influence each other mutually because of intersecting pathology.
| Item Type: | Thesis (Masters) |
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| Additional Information: | Reg.No.200120505501 |
| Uncontrolled Keywords: | Thyroid Dysfunction, Type 2 Diabetes Mellitus. |
| Subjects: | MEDICAL > General Medicine > MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 17 Aug 2021 08:17 |
| Last Modified: | 28 Apr 2024 01:32 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/17971 |
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