Govindaraju, M (2020) Functional Outcome and Time Taken for Consolidation in Giant Cell Tumor after Fibular Strut Grafting Based on Intratumor Cavity Volume: A Retrospective and Prospective study. Masters thesis, Madras Medical College, Chennai.
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Abstract
BACKGROUND: Giant cell tumor is one of the commonly encountered bone tumor in the field of orthopaedics. Giant cell tumor represents around 4-5% of all primary bone tumors The neoplasm is most common in the age group of 20 to 40. Nearly 70% of the cases fall within this age group. AIM OF THE STUDY: Aim of the study is to analyse the functional outcome and time taken for consolidation of Giant cell tumor after fibular strut grafting based on intra tumor cavity volume. MATERIAL AND METHODS: In our study 11 patients with tissue diagnosis of gaint cell tumor were included. Of the 11 patients 6 were females and 5 were males all were in the mean average age group of 30 years (18-39), all were treated with curettage and fibular strut grafting with zoledronic acid adjuvant. Before surgery tumor volume was measured using CT or MRI by Ellipsiod volume calculation method .Then post operatively functional outcome and time taken for consolidation of the tumor cavity was analysed using follow up radiographs. RESULTS: The average tumor volume was 92 cm3. The average time taken for consolidation was 18 weeks. Of the 11 patients, 5(100%) patients whose tumor size is less than 92cm3 consolidated within 18 weeks. 6 patients were taken more than 18 weeks, among the 6 patients 4(67%) were consolidated more than 92 cm3. Remaining 2(33%) were less than 92cm3. The chi square values were significant when p is <0.05, which shows that period of consolidation was based on size of the tumor. Conclusion Our study demonstrates that tumor volume of less than 92 cm3 consolidated earlier at an average period of less than 18 weeks. Tumor volume of more than 92 cm3 consolidated after 18 weeks with maximum period of 24 weeks. There was no collapse of the cavity in our serial follow up despite filling the cavity only with fibular strut graft .Neither bone cement nor cancellous bone graft were used. High quality, efficient healing and nil recurrence of Giant cell tumor were achieved after treating with curettage and fibular strut graft with zoledronic acid adjuvant.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 221712003 |
| Uncontrolled Keywords: | Functional Outcome, Time Taken for Consolidation, Giant Cell Tumor, Fibular Strut Grafting, Intratumor Cavity Volume, Retrospective and Prospective study. |
| Subjects: | MEDICAL > Orthopaedics |
| Depositing User: | Subramani R |
| Date Deposited: | 13 Feb 2021 12:10 |
| Last Modified: | 13 Feb 2021 12:10 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14088 |
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