Rajadurai, M (2019) A Comparative study in Efficacy of Ultrasound Guided Autologous Platelet Rich Plasma and Corticosteroid Injection in Lateral Epicondylitis. Masters thesis, Kilpauk Medical College, Chennai.
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Abstract
BACKGROUND: Lateral epicondylitis is referred to a degenerative disorder that affects the common extensor tendon where it attaches to the lateral epicondyle of the humerus. Platelet rich plasma and corticosteroid injection have both been suggested to treat chronic lateral epicondylosis. Nowadays, one of minimally invasive interventions is platelet rich plasma injection that had been explored in some controlled clinical studies to show its effectiveness in treating lateral epicondylitis through inducing inflammation rather than suppressing it. AIMS AND OBJECTIVES: 1. To assess the efficacy of ultrasound guided autologous platelet rich plasma and corticosteroid injection. 2. To compare autologous platelet rich plasma Vs corticosteroid injection in terms of efficacy and its functional outcome. MATERIALS AND METHODS: 220 patients with chronic lateral epicondylosis were randomly selected on lot basis and divided into two groups. 110 patients injected with 2ml of platelet rich plasma and 110 patients injected with 2ml of corticosteroids injection through peppering needle technique. Pain and functional improvements were assessed using visual analogue scale. RESULTS: Baseline evaluation showed no difference between the two groups. Analysis at 2 weeks showed significant decrease in VAS score in favour of corticosteroid group. Evaluation at 24 weeks demonstrated a statistically significant difference between groups favouring PRP group (p < 0.05). CONCLUSION: PRP and corticosteroids injection are safe and effective in treatment of lateral epicondylosis. Corticosteroids are effective on short term period. However, on long term follow-up, PRP seems to be the more effective treatment with more persistent efficacy than corticosteroid in relieving pain.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Lateral epicondylosis, platelet rich plasma injection, corticosteroid injection. |
| Subjects: | MEDICAL > Orthopaedics |
| Depositing User: | Subramani R |
| Date Deposited: | 01 Sep 2019 10:41 |
| Last Modified: | 01 Sep 2019 10:41 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/11368 |
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