Bharathi, T (2019) Observational Study of Medulloblastoma, Barnard Institute of Radiation Oncology, Madras Medical College, Chennai From 2001 to 2010. Masters thesis, Madras Medical College, Chennai.
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Abstract
AIM OF THE STUDY: To study the long term outcome of medulloblastoma patients, who were treated in our institution during the period 2000-2010.It is a retrospective study. 1. Age and sex distribution, 2.tumor location, 3. clinical presentation, 4. treatment modalities and 5. the response to treatment. Criteria’s of inclusion, 1) biopsy proven medulloblastoma patients. 2) registered in department of radiation Oncology, RGGGH, Chennai, 3) The treatment period Jan 2000 - Dec2010. Gender distribution: Among the 75 cases reported, 42 males (56%) and 33 females (44%.). Clinical presentation: Head ache(78%) ,vomiting (73%), Seizures (9.3%), of treatment completed patients < % of patients with incomplete treatment. Defaulters: surgery is the arm -13 % In radiotherapy arm- 37.4% The chemotherapy arm -33 %. Reason of treatment default: 1. Lack of awareness about different modalities (42%) that should be incorporated. 2. False belief of poor outcome of patient in the treatment (28%). 3. Fear of toxicity. 4. Lack of adequate follow up facility. RECURRENCE: Out of total 75 patients, 7 had recurrence (3 loco regional and 4 distant recurrence). QUALITY OF LIFE ASSESSMENT: QLQ – C30 version of EORTC). Ideas about life partner - 80%, Difficulty in learning - 69%, Interpersonal relationship - 62%, Cosmetic disfigurement - 33%, Aggressive nature, irritable – 33%, Visual impairment - 25%, Sports activities - 0%. CONCLUSION: Although medulloblastoma is a tumor of high mortality, correct treatment with surgery, chemotherapy and radiotherapy can save the life of the patient to certain extent. Medulloblastoma special clinics must be created so that the patients are enrolled in the clinic and adequate treatment follow up is ensured.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Medulloblastoma, Barnard Institute of Radiation Oncology, Madras Medical College, Chennai, Observational Study. |
| Subjects: | MEDICAL > Radio Therapy |
| Depositing User: | Subramani R |
| Date Deposited: | 19 Aug 2019 03:15 |
| Last Modified: | 19 Aug 2019 03:15 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/11056 |
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