Shahbaz Zailu Mohamed, - (2017) Association of dietary sodium and potassium with blood pressure in a tertiary care centre. Masters thesis, Sree Mookambika Institute of Medical Sciences, Kulasekharam.
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Abstract
BACKGROUND AND OBJECTIVES: Hypertension is a leading cause for Non Communicable diseases. The aim was to study the association of dietary sodium and potassium as estimated from the urinary excretion of these cations with blood pressure. METHODS: Institutional Human Ethical committee clearance was obtained. After taking an informed consent, 260 patients were enrolled in the study which included 130 hypertensives and 130 non-hypertensives. All the subjects were in the age group of 30 to 79 years. A random clean catch urine sample was collected for estimation of sodium and potassium and routine blood tests for hypertension workup were done. The 24 hour urine sodium and potassium was estimated from the spot samples using the Kawasaki formula. Data collected was analysed by SPSS version 20.1 RESULTS: The average systolic BP among the non-hypertensives was 117.6 ± 9.05 and average diastolic blood pressure was 72.15 ± 6.93. The average systolic blood pressure among the hypertensives was 143.3 ± 15.1 and average diastolic blood pressure was 90.92 ± 7.41. The average urinary sodium excretion in 24 hrs among non- hypertensives was 5131.49 ± 1013.65 mg/d and among hypertensives was 6343.05 ± 2362.73 mg/d. The average urinary potassium excretion in 24 hrs among the non-hypertensives was 2100.72 ± 476.47 mg/d and among hypertensives was 2291.61 ± 534.93 mg/d. The mean ratio of 24 hr urinary excretion of sodium to 24 hr urinary excretion of potassium was 2.51 ± 0.55 in the non-hypertensive group and 2.72 ± 0.59 mg/d in the hypertensive group. There was a positive correlation between the daily urinary sodium, urine potassium and 24 hr urine sodium-potassium ratio with systolic and diastolic BP among the hypertensives. There was no significant correlation among the non-hypertensives. CONCLUSIONS: In a developing country like India to control the menace of hypertension, modifiable risk factors like dietary salt intake need to be controlled. Government policy makers and NGOs should work together to conduct salt reduction programmes to create awareness among the public and avert premature death and disability.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Hypertension ; Urinary sodium ; Urinary potassium. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 25 Nov 2018 01:29 |
| Last Modified: | 25 Nov 2018 01:29 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/10105 |
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