Ponmudi, C (2019) Development of Antimicrobial Activity of Senna Alata Linn Niosomal Gel. Masters thesis, K. M. College of Pharmacy, Madurai.
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Abstract
An effort was made to formulate the Senna alata Niosomes and incorporate the Niosomes into the gel. From the results of the present experiments it may be concluded that formulation F6 showing high percentage of entrapment and desired sustained release of Senna alata Niosome gel. Hence F6 formulation was optimized one. The optimized formulation F6 was found to follow zero order release pattern which was revealed by the linearity shown from the plot of time versus concentration. Niosomes were stable for 4 weeks at 40 C and affirm the drug leakage increased the higher temperature. Optimized formulation was released from the Niosomal gel formulation in a sustained manner for 24 Hours. The present work revels that the senna alata niosomal gel produces anticipated synergistic effect against most of the tested fungal strain. So, my work revels that the formulated Antimicrobial niosomal gel will shows the benefit to society against opportunistic fungal and bacterial infection. Antimicrobial activity indicates that the gel preparation of the optimized formulation F6 Thus, the aim of the project was achieved by optimizing the formulation Parameters. Antimicrobial sensitivity screening, the ethanolic extract of Senna alata niosomal gel showed excellent activity and Most of these organisms are natural flora of the skin. Hence, plant based medicines that inhibit their growth without harming the host represent potential therapeutic agent.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 261710102 |
| Uncontrolled Keywords: | Antimicrobial Activity, Senna Alata Linn Niosomal Gel |
| Subjects: | PHARMACY > Pharmaceutics |
| Depositing User: | Ramakrishnan J |
| Date Deposited: | 20 May 2022 05:42 |
| Last Modified: | 20 May 2022 05:42 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/20129 |
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