A Study of Serum Sodium Level and Its Prognostic Significance in Patients with Acute Stemi in Tertiary Care Center

Cauvery, N (2023) A Study of Serum Sodium Level and Its Prognostic Significance in Patients with Acute Stemi in Tertiary Care Center. Masters thesis, Thanjavur Medical College, Thanjavur.

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Abstract

INTRODUCTION: Following a Myocardial Infarction, hyponatremia is frequent, and a rise in plasma sodium contents coincides with clinical recovery. Hyponatremia was present in about one third of the congestive heart failure patients. It has been demonstrated that in patients with heart failure and STEMI, it is a predictor of cardiovascular death. Acute STEMI patients who presented with hyponatremia at the time of admission and within 72 hrs of admission had high mortality and so serum sodium level (hyponatremia) is a prognostic indicator. Patient at risk can be identified by a simple marker of plasma sodium level. OBJECTIVES: To study the prognostic importance of serum sodium level (hyponatremia) among 80 patients with acute STEMI. METHODOLOGY: This is a Cross sectional analytical study, among 80 patients admitted with acute STEMI under the Department of General Medicine, Thanjavur Medical College and hospital, Thanjavur. Relevant history, clinical findings, biochemical measurements especially the serum sodium levels were compared with the outcomes. Prognostic value of the serum sodium levels were analyzed. RESULTS: Among the subjects, 71 (88.75%) were Recovered and 9 (11.25%) had Death. The mean Serum Sodium at admission, at 24 hours, at 48 hours and 72 hours (mEq/L) among Death was lower and statistically significant compared to the Recovered. Serum Sodium on admission, at 24 hours, at 48 hours and 72 hours in predicting Death was significant, with the good diagnostic accuracy value. CONCLUSION: Serum sodium can be used as a prognostic parameter for predicting death among the acute STEMI patients. The role of correction of the hyponatremia in prevention of the mortality rate among the acute STEMI patients’ needs to be explored.

Item Type: Thesis (Masters)
Additional Information: Reg.No.200120102502
Uncontrolled Keywords: Serum sodium level, Hyponatremia, Acute coronary syndrome, Myocardial infarction, acute STEMI.
Subjects: MEDICAL > General Medicine
> MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 15 May 2021 13:09
Last Modified: 24 Mar 2024 02:32
URI: http://repository-tnmgrmu.ac.in/id/eprint/16784

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