Soundarya, B (2020) Estimation of Salivary Estradiol and Salivary Calcium in Post Menopausal Women With or Without Xerostomia. Masters thesis, Ragas Dental College and Hospital, Chennai.
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Abstract
AIM OF THE STUDY: The aim of our study is to evaluate salivary estradiol and salivary calcium in post menopausal women with varying degree of oral dryness. MATERIALS AND METHODS: The study included 60 women between 25-60 years of age. Group I consisted of healthy menstruating women between 25-35 years of age. In group II premenopausal women between 35-45 years of age were present and group III consisted of menopausal women between 45-60 years of age.Unstimulated saliva was collected from the participants and estradiol analysis was done using ELISA method and calcium analysis was done using Arsenazo III reaction using colorimetric method. The oral health status in these patients was determined by using oral hygiene index, Russell’s periodontal score and xerostomia score. The values of the above said parameters were subjected to statistical analysis and the results were derived. RESULTS: Salivary estradiol levels were low in 95% of the postmenopausal women and in premenopausal women it was normal in 90% of the cases and decreased in 10% of the cases. Salivary calcium was high in 45 % and low in 35% and normal in 25% of the postmenopausal women. In premenopausal women, it was normal in 10% of the subjects and low in 90% of the subjects. The Russell’s periodontal score of the postmenopausal group 10% had beginning destructive periodontal disease,70% had established destructive periodontal disease 15% had terminal periodontal disease.95% of postmenopausal women had poor oral hygiene while on 5% has good oral hygiene. Xerostomia was evaluated among the groups and it was found premenopausal women exhibited mild to moderate levels of xerostomia while postmenopausal women exhibited severe levels of xerostomia.In menopausal group, it was found as salivary estradiol levels decreases there was an increase in xerostomia scores and salivary calcium. It was also found that as salivary calcium levels increased the periodontal scores increased. All parameters were within normal limits among healthy menstruating women. CONCLUSION: Saliva can be a preferred medium and an emerging alternative for serum to estimate estradiol and calcium levels. As a dentist, we have to educate them about the oral changes they will experience during menopause and emphasize its strong association between low oestradiol levels. Oral hygiene instructions should be given for maintenance of healthy periodontium.Menopausal women who experience severe postmenopausal symptoms can be identified and the dentist and gynecologist can work hand in hand to treat the symptoms of these women.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Salivary estradiol, salivary calcium, menopause, xerostomia, periodontitis, oral hygiene. |
| Subjects: | DENTAL > Oral Medicine and Radiology |
| Depositing User: | Subramani R |
| Date Deposited: | 25 Feb 2021 03:12 |
| Last Modified: | 25 Feb 2021 16:34 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14518 |
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