Srishti, Ramamurthy (2020) Analysis of Tear Film Pre and Post Lasik Using Oculus Keratograph 5M in a Tertiary Eye Care Center. Masters thesis, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai.
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Abstract
AIM OF THE STUDY: To study the tear film (Non Invasive Keratograph Tear break-up time- NIKBUT and Tear Meniscus Height - TMH) preoperatively and postoperatively (1 month follow up visit) using Oculus Keratograph 5M in all patients undergoing LASIK (Mechanical microkeratome and Femtosecond laser) during the time period of the study in the Cornea department, Aravind Eye hospitals, Madurai. MATERIALS AND METHODS: Prospective observational study to quantify changes in tear film parameters post LASIK. Demographic data, average TMH values, NIKBUT Average, Schirmer’s test and subjective OSDI questionnaire were documented pre-operatively and at the 1 month post-operative follow up. Intraoperative flap thickness and post-operative medications were also noted. Comparison of outcomes between Mechanical Microkeratome and Femtosecond Laser assisted LASIK was done. Statistical analysis was done with STATA 14.1 (Texas, USA). p value < 0.05 was considered significant. RESULTS: 130 patients with a mean age of 23.74 (3.20) years were included. TMH (p value 0.002) and NIKBUT (p=0.0005) measured using Oculus Keratograph 5M and Schirmer’s test (p value 0.003) showed a significant decrease post-operatively. Subjective OSDI questionnaire did not show a significant change post-operatively. There was no significant difference on comparing tear film parameters between patients who underwent Mechanical Microkeratome and Femtosecond LASIK. CONCLUSION: Objective measurements of tear film parameters quantified using Oculus Keratograph 5M and Schirmer’s test decreased post-operatively at 1 month follow up. These parameters did not correlate with the lack of subjective symptoms post-operatively documented using OSDI. Longer follow up period would aid in detecting occurrence of chronicity of dry eye post-LASIK.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 221713460 |
| Uncontrolled Keywords: | Oculus keratograph 5M, LASIK, dry eye, tear film, TMH, NIKBUT, Schirmer, OSDI. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Subramani R |
| Date Deposited: | 14 Feb 2021 16:33 |
| Last Modified: | 14 Feb 2021 16:33 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14211 |
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