Ravichandran, R (2014) Clinical and Electrophysiological profile of vestibular function in Parkinson Disease. Masters thesis, Madras Medical College, Chennai.
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Abstract
Postural instability, dysequilibrium, freezing of gait and the consequential falls are among the most disabling manifestations of Parkinson’s disease. Postural instability in PD results from abnormalities in sensorimotor integration. The role of vestibular otolith function in dysequilibrium in PD is still not clear. We assessed the clinical profile and vestibular evoked myogenic potential (VEMP) in patients with Parkinson disease. We have found that bilaterally absent VEMPs are a pointer to the otolithic vestibular dysfunction in patients with Parkinson’s disease. Peak latencies of the p13 and n23 are not prolonged in patients with Parkinson’s disease and VEMPs in patients with Parkinson’s disease seem to follow an “all or none” response either with a present or absent response. Cervical VEMPs in patients with Parkinson’s disease correlate significantly with falls and postural instability. Cervical VEMPs may serve as a predictor or marker of falls and postural instability in patients with Parkinson’s disease. CONCLUSION : The abnormalities in the vestibular system particularly of the otolith component could contribute to the disequilibrium in patients with Parkinson’s disease. Based on our observations and analysis we conclude,
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Parkinson Disease ; vestibular function ; Clinical and Electrophysiological profile. |
| Subjects: | MEDICAL > Neurology |
| Depositing User: | Kambaraman B |
| Date Deposited: | 30 Jun 2017 02:42 |
| Last Modified: | 30 Jun 2017 05:45 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/671 |
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