Design and Development of Fast Dissolving Tablets of Felodipine Using Different Methods

Bavikar Jagdishchandra, Vinayak (2012) Design and Development of Fast Dissolving Tablets of Felodipine Using Different Methods. Masters thesis, J.K.K. Nattraja College of Pharmacy, Komarapalayam.

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Abstract

The Oral route of administration still continues to be the most preferred route due to its manifold advantages including ease of ingestion, pain avoidance, versatility and most importantly patient compliance. Therefore, oral solid dosage forms are popular because of ease of administration, accurate dosage, self medication, pain avoidance and most importantly patient compliance. Among the pharmaceutical dosage forms, the conventional tablets seem to be most popular, because of its ease of transportability and comparatively lower manufacturing cost. From this study, it can be concluded that dissolution rate of felodipine could be enhanced by tablets containing solid dispersion and sublimation technique. Tablets prepared by sublimation method showed least disintegration times as compared with other tablets prepared by solid dispersion method. Tablets prepared by sublimation method showed best dissolution rate than the other tablets prepared by solid dispersion method. Here we have succeeded in formulating fast dissolving formulation for Felodipine which are cost effective and have patient compliance. Success of the present study recommends a detailed investigation in to invivo studies for its effective use in clinical practice.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Design ; Development ; Dissolving Tablets ; Felodipine ; Different Methods.
Subjects: PHARMACY > Pharmaceutics
Depositing User: Ravindran C
Date Deposited: 23 Jun 2017 08:45
Last Modified: 15 May 2018 23:45
URI: http://repository-tnmgrmu.ac.in/id/eprint/347

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