Kavitha, M (2014) To determine the association of risk factors in type 2 diabetic patients with diabetic macular ischemia. Masters thesis, Stanley Medical College, Chennai.
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Abstract
AIM:-To determine the association of risk factors in type 2 diabetic patients with diabetic macular ischemia. Materials and methods:-A cross sectional study was performed on 100 diabetic patients attending the out patient department of ophthalmology, govt Stanley medical college,Chennai, during the period November 2012 to October 2013. Patients who filled the inclusion criteria were included in the study. Detailed history about systemic medical illness and ophthalmic history were elicited. Ophthalmic examination included V/A,refraction, slit lamp examination of the anterior segment, IOP and fundus examination. Diabetic retinopathy graded according to the abbreviated ETDRS severity scale. Fundus fluorescein angiography done and diabetic macular ischemia graded according to the criteria followed by bresnick et al. Systemic examination included BP recording, lab investigations FBS, PPBS, HbA1c, lipid profile,urine routine,ECG done. Significance of associations are analysed using chi square test and all the significant variables in univariate analysis were included in the multivariate analysis to calculate adjusted odds ratio for the individual factors. Results:- The association of diabetic macular ischemia with nephropathy and uncontrolled DM were found to be statistically significant (OR 4.5, 95% CI 1.8-11.0, P value .001); (OR 2.9, 95% CI 1.2-7.4, P value .02) respectively,the association of other variables age,gender,duration of DM, HTN, IHD, hyperlipidaemia were p value 0.912,0.500, 0.539, 0.554, 0.476, 0.201 respectively not found to be significant. 9/13 eyes (69.23%) in severe;13/22eyes (59.1%) in moderate; 1/6 eyes(16.7%) in mild diabetic macular ischemia showed decreased visual acuity. Conclusion:- In our study the most significant associated factor was nephropathy followed by uncontrolled diabetes and the other factors like duration of DM, HTN, IHD, hyperlipidaemia were not as significantly associated as nephropathy. Also we found that visual acuity is more affected in severe grades of diabetic macular ischemia and preserved in milder grades of diabetic macular ischemia.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | diabetic macular ischemia; fundus fluorescein angiography; HbA1c; diabetes mellitus; hypertension; IHD; hyperlipidaemia; risk factors; visual acuity; odds ratio |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Devi S |
| Date Deposited: | 14 Sep 2017 06:33 |
| Last Modified: | 14 Sep 2017 06:33 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/3146 |
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