Amarnath, M (2012) Phytochemical Screening, Isolation, and Characterization & Biological Evaluation of Ethanolic Extract of Nelumbo Nucifera Leaf. Masters thesis, College of Pharmacy, Madurai Medical College, Madurai.
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Abstract
Herbal medicines are in great demand in the developed world for primary health care due their efficacy, safety and lesser side effects. Recently ,considerable attention has been paid to utilize eco-friendly and bio –friendly plant based products. The natural products are undoubtedly valuable as a lead for new medicinal agents. Hence in the present study, is to investigate the Anti-inflammatory (carregeenan induced paw edema method) and Anti-microbial efficacy for the Ethanolic extract of leaves of Nelumbo nucifera. Herbal medicines are in great demand in the developed world for primary health care due their efficacy, safety and lesser side effects. Recently ,considerable attention has been paid to utilize eco-friendly and bio –friendly plant based products. The natural products are undoubtedly valuable as a lead for new medicinal agents. Hence in the present study, is to investigate the Anti-inflammatory (carregeenan induced paw edema method) and Anti-microbial efficacy for the Ethanolic extract of leaves of Nelumbo nucifera. The plant Nelumbo nucifera was highly praised for its beauty and ornamental values, yet it is highly considered for its medicinal values. Various parts of the plant like leaf, flower, seeds and rhizomes were subjected for various in-vivo and in-vitro activities, it shows excellent pharmacological actions on the diseases like obesity, hyperlipdemia, various cancers, anti-HIV and various anti-bacterial activities. In present study, crude ethanolic extract of leaf of NN was subjected for the isolation of a probable flavonoid compound, which was characterised using spectral data’s. The compound posses potential DPPH radical scavenging activity, which was further evident for the anti-inflammatory effect of the crude extract using carragenam induced paw oedema method. The extract was also investigated for its Anti-microbial activity, particularly for (MRSA), which is highly resistant for various anti-biotic. From the results obtained, it may be concluded that extract of leaf of NN, could reduce the inflammation and considered for its anti-microbial activity. It seems promising that these data will be validated in the future molecular level studies to establish its potential medicinal values.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Phytochemical Screening; Isolation; Characterization; Biological Evaluation; Ethanolic Extract;f Nelumbo Nucifera Leaf |
| Subjects: | PHARMACY > Pharmaceutical Chemistry |
| Depositing User: | Ravindran C |
| Date Deposited: | 17 Aug 2017 07:54 |
| Last Modified: | 17 Aug 2017 07:54 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/2671 |
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