A Prospective Clinicopathological study and Management of Benign Lesions of Larynx

Jayalekshmi, P A (2022) A Prospective Clinicopathological study and Management of Benign Lesions of Larynx. Masters thesis, Thanjavur Medical College, Thanjavur.

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Abstract

INTRODUCTION: Larynx the "voice box" is an important organ of the body. It protects lower respiratory tract, provides a controlled airway, allows phonation and generation of high intrathoracic pressure for coughing and lifting. The powerhouse or generator of voice is infraglottic tract which puts into vibration of true vocal folds creating buzzing sound which is amplified and given a significant character by supraglottic vocaltract. Even without the help of language, voice helps in expressing emotions. It helps to express the mood and attitude. For professional voice users like singers the quality of voice is very significant. PRIMARY OBJECTIVES: The present study on non malignant lesions of larynx is undertaken to study — The incidence and distribution of cases according to age, sex, etiology, occupation etc. 1. To study pathophysiology of the disease To study symptomatology of benign lesions of larynx To study about various diagnostic tools and modalities of treatment available. 2. To study prognosis of the most frequent benign lesions of larynx along with follow up of the patients upto 6 months after treatment. MATERIALS AND METHODS: This is a study conducted in the Thanjavur Medical College, Department of Otorhinolaryngology between January 2020 – july 2021 . Thanjavur we receives a number of referred cases from all nearby district headquarters Govt. Hospitals. We analysed 30 patients with benign lesion of larynx incuding both neoplastic and nonneoplastic lesions and selected patients with persistent hoarseness or other vocal symptoms for more than three weeks. All patients underwent a complete ENT examination and once suspected, that patients were examined under direct laryngoscope or fibreoptic laryngoscope and if needed microlaryngeal examination was also done. Benign non neoplastic lesions were treated by speech therapy, voice rest, LASER, or excision biopsy and confirmed with biopsy results. The benign neoplastic lesions underwent direct laryngoscopic examination and routine x-rays . If needed CT scan was done. The deserved cases underwent surgical procedures and management results were analysed. We analysed with all this information and obtained the aim of the study. INCLUSION AND EXCLUSION CRITERIA : Inclusion criteria: All patients in the age group of 15-65 years of both sexes with manifestations of benign lesions of larynx, who presented to the ENT OPD from January 2020 to July 2021. Exclusion Criteria: All patients with lesions of larynx that showed features of malignancy, CNS pathology and all critically ill patients where excluded. CONCLUSION: 90% of the benign lesions observed in larynx non-neoplastic type. Vocal nodule was the commonest benign non-neoplastic lesion while papilloma was the commonest neoplastic lesion observed in adults and in children Recurrent Respiratory Papillomatosis was the commonest. The most common symptom was hoarseness followed by vocal fatigue and reduced vocal range. Vocal abuse was the predisposing factor in vocal nodules. Smoking was the major predisposing factor for vocal polyp. Previous history of endotracheal intubation predisposed to vocal granuloma formation. The most commonly done examination procedure in OPD was Indirect laryngoscopy and the most useful investigation of choice was video laryngoscopy and stroboscopy. The most common surgical modality of treatment was Microlaryngeal excision. As far as morbidity is concerned prognosis is good. Recurrent respiratory papillomatos, trauma have poor prognosis as some morbidity is always there. All lesions when treated early and completely and followed up properly with voice rest have very good prognosis.

Item Type: Thesis (Masters)
Additional Information: 221914203
Uncontrolled Keywords: Benign Lesions of Larynx, Management, Prospective Clinicopathological study.
Subjects: MEDICAL > Otolaryngology
> MEDICAL > Otolaryngology
Depositing User: Subramani R
Date Deposited: 12 May 2021 16:24
Last Modified: 17 Dec 2023 11:16
URI: http://repository-tnmgrmu.ac.in/id/eprint/16519

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