Gokulakrishnan, V (2017) A Study on Prognostic Implication of Hs-CRP In Acute Coronary Syndrome (ACS) patients admitted in Thanjavur Medical College & Hospital. Masters thesis, Thanjavur Medical College, Thanjavur.
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Abstract
AIMS AND OBJECTIVE: To evaluate the prognostic implication of Hs-CRP in Acute coronary syndrome (ACS) patients admitted in Thanjavur Medical College & Hospital (TMCH). STUDY DESIGN: The study was designed as a prospective biochemical study. METHODOLOGY: 48 acute coronary syndrome patients (both STEMI & NSTEMI) between 25-75 years of age and of both sex, who were admitted in Thanjavur Medical College and Hospital, ICCU&IMCU were included in our study. Based on the clinical presentation, ECG findings and positivity for the cardiac biomarker troponin -T, the diagnosis of acute coronary syndrome (ACS) was established. 7ml of venous blood samples were collected from ACS patients under aseptic conditions and the highly sensitive C reactive protein (Hs-CRP) levels were estimated within 6 hours of admission (baseline) and between 36-48 hours (peak value) of admission. All the 48 acute coronary syndrome (ACS) patients underwent thrombolytic therapy and they were fully interrogated and investigated during the 1 week hospital stay. RESULTS: Pearson’s correlation analysis was done to assess the relationship between baseline and peak values of Hs-CRP and body mass index, lipid profile and Ejection fraction. There was a statistically significant correlation (p < 0.05) between prognosis and Hs-CRP level with a p-value of 0.001 in our study. CONCLUSION: Patients with elevated levels of Hs-CRP had a poor prognosis. Hence, the assessment of Hs-CRP levels may enable the physician in detecting the prognosis of acute coronary syndrome patients and in planning a more prompt and effective reperfusion therapy.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Highly sensitive C- reactive Protein (HsCRP), Acute Coronary Syndrome (ACS), ST- elevation myocardial infarction (STEMI), Non-ST- elevation myocardial infarction (NSTEMI). |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 27 Feb 2020 03:50 |
| Last Modified: | 27 Feb 2020 17:40 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/12036 |
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