A Clinical study of hemangiomas and vascular malformations.

Vidya Lakshmi, S (2010) A Clinical study of hemangiomas and vascular malformations. Masters thesis, Madras Medical College, Chennai.

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Abstract

INTRODUCTION : A hemangioma is an abnormal proliferation of blood vessels that may occur in any vascularized tissue. Considerable debate exists as to whether these lesions are neoplasms, hamartomas, or vascular malformations. Mulliken strongly supports classification of hemangiomas as neoplasms1, whereas Godanich and Capanacci2 seem to favor a hamartomatous classification. There seems to be consensus that the term "hemangioma" should refer to "hemangiomas of infancy," which have a predictable natural history that includes absence at birth followed by a period of growth over 6-18 months and then a period of involution that may take several years3. Vascular malformations have been recognized throughout history as birthmarks. The cause was thought to be maternal cravings for fruit or maternal dreams, moods, and fantasies. Although Blondel disproved these theories in 1727, some persist today. In 1866, Dugas conducted a scientific analysis of birthmarks and concluded that they were caused by defects in embryonic development. Virchow and Wagner established the first classification system of vascular malformations, based on channel architecture and histomorphologic appearance. AIM OF THE STUDY : 1. To study the incidence of hemangiomas and vascular malformations. 2. To study the age of onset of hemangiomas and vascular malformations. 3. To study the sex distribution of hemangiomas and vascular malformations. 4. To study the familial incidence of hemangiomas. 5. To study the distribution of lesions. 6. To study the complications. 7. To study the associations. CONCLUSION : Hemangiomas and vascular malformations were a rare occurrence constituting only 0.11% of all new cases attending the Dermatology outpatient department during the study period. * The incidence of hemangiomas was almost twice as much as that of vascular malformations. * Most of the hemangiomas had onset at birth while all vascular malformations were present since birth. * Hemangiomas had a female predominance, while in vascular malformations there was almost an equal sex distribution. * Familial incidence of hemangiomas was encountered in 11.11% cases. * The most common site of occurrence in hemangioma was head and neck followed by trunk, extremities, and genitalia; while in vascular malformation face was the most commonly involved site followed by extremities and trunk. * Hemangiomas commonly presented with single lesion, and most cases were either in progressive or non involuting phase. Multidermatomal involvement was observed more often in vascular malformations. * Localized type of hemangiomas was most commonly observed while segmental type was most commonly associated with complications. * Port wine stain occurred most commonly over the distribution of maxillary division of trigeminal nerve. Patients with CNS or ocular complications or both had preferential involvement of maxillary branch. * Most frequently encountered complication in hemangiomas was ulceration followed by bleeding, feeding difficulty and vision impairment. In vascular malformations, seizures and glaucoma were the complications noted. * Complications of hemangiomas were found to be common among children born either preterm or low birth weight or both. * Hydrocephalus and subglottic involvement was noted in 2 cases of hemangioma; while 3 cases of Phakomatosis pigmentovascularis and 2 cases of Klippel Trenaunay were observed in patients with vascular malformation.

Item Type: Thesis (Masters)
Uncontrolled Keywords: hemangiomas ; vascular malformations ; clinical study.
Subjects: MEDICAL > Dermatology Venereology & Leprosy
Depositing User: Subramani R
Date Deposited: 05 Jul 2017 05:29
Last Modified: 05 Jul 2017 05:29
URI: http://repository-tnmgrmu.ac.in/id/eprint/987

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