Seroprevalence of Herpes Simplex Virus 1 and 2, Hepatitis B and Chlamydia Trachomatis among the Patients attending Sexually Transmitted Diseases Department.

Subha, G (2010) Seroprevalence of Herpes Simplex Virus 1 and 2, Hepatitis B and Chlamydia Trachomatis among the Patients attending Sexually Transmitted Diseases Department. Masters thesis, Madras Medical College, Chennai.


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INTRODUCTION : Sexually transmitted diseases (STDs) are a major cause of morbidity in developed as well as developing countries. STD incidence rates remain high in most of the world, despite diagnostic and therapeutic advances that can rapidly render patients with many STDs noninfectious and cure most. In 1996, the World Health Organization estimated that more than 1 million people were being infected daily. About 60% of these infections occur in young people <25 years of age, and of these 30% are <20 years. Between the ages of 14 and 19, STDs occur more frequently in girls than boys by a ratio of nearly 2:1; this equalizes by age 20. An estimated 340 million new cases of syphilis, gonorrhoea, chlamydia and trichomoniasis occurred throughout the world in 1999. Centre for Diseases Control and Prevention (CDC) has estimated that nearly 20 million STD cases occur every year, with half among people less than 25 years. Changing cultural values, changing sexual morals, increase in travel, all had contributed for increase in STDs. Additionally, development and spread of drug resistant bacteria (e.g., penicillinresistant gonococci) makes some STDs harder to cure. Commonly reported prevalence of Sexually Transmitted Infections (STI) among sexually active adolescent girls both with and without lower genital tract symptoms include Chlamydia (10–25%), gonorrhoea (3–18%), syphilis (0–3%), Trichomonas vaginalis (8–16%), and herpes simplex virus infection (2–12%). Among adolescent boys with no symptoms of urethritis, isolation rates include chlamydia (9– 11%) and gonorrhea (2–3%). AIM OF THE STUDY : To determine the seroprevalence of Herpes Simplex virus (HSV1 and HSV2), Hepatitis B and Chlamydia trachomatis among the patients attending the outpatient department of Institute of Venerology, Madras Medical College. CONCLUSION : The seroprevalence of HBsAg is 6.5%, Herpes simplex virus 1 antibodies is 50.5%, Herpes simplex virus type 2 antibodies is 45.05% and Chlamydial antibody is 38.46%. * Most of the HSV antibodies are of IgG type indicating past infection. * Infection with one STI increases the risk of acquiring other STIs. 42.8% of the patients studied had co infections. * HSV 1 and HSV 2 are the most common co infections. * The seroprevalence of HIV in this study is 10.9%. HSV 2 and Chlamydia are the most common co infections in patients with HIV. * The prevalence of HSV 1 and 2 antibodies and Chlamydial antibodies are high in asymptomatic patients. * Most of the seropositive patients in this study are married, educated upto secondary school and urban residents.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Seroprevalence ; Herpes Simplex Virus 1 and 2 ; Hepatitis B ; Chlamydia Trachomatis ; Patients.
Subjects: MEDICAL > Dermatology Venereology and Leprosy
Depositing User: Subramani R
Date Deposited: 05 Jul 2017 05:10
Last Modified: 05 Jul 2017 09:13

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