Menaka, C (2015) Study on the role of mitomycin C in the Management of ocular surface squamous neoplasia. Masters thesis, Madras Medical College, Chennai.
|
Text
220300115menaka.pdf Download (14MB) | Preview |
|
|
Text
220300115menaka_abstract.pdf Download (8kB) | Preview |
Abstract
AIM OF THE STUDY: 1. To evaluate the role of Mitomycin C as an adjuvant therapy intraoperatively and post operatively in the management of Ocular Surface Squamous Neoplasia. 2. To determine the role of Mitomycin C in the prevention of recurrence of Ocular Surface Squamous Neoplasia. METHOD: The proposed study is a prospective Study conducted in 20 patients. After surgical excision intraoperatively 0.4mg/ml of Mitomycin c applied over the excised site for 3-4 minutes. Postoperatively 2 cycles of 0.04% Mitomycin c eye drops 4 times per day was given approximately 2 weeks after the surgical excision, each cycle lasting for 1 week with off period of 1 week in between.Antibiotic steroid eyedrops given throughout the postoperative period. RESULTS: Among the 20 patients studied 19 showed good outcome and no Recurrence over the period of 12 months observation. 1 patient developed Recurrence. only 2 patients had short limiting complications. No long term and systemic complications. CONCLUSION: Intraoperative and postoperative use of mitomycin c is effective in the management of OSSN and is quite effective in preventing the recurrence.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | ocular surface squamous neoplasia : mitomycin C ; Management. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Devi S |
| Date Deposited: | 06 Oct 2018 15:32 |
| Last Modified: | 06 Oct 2018 15:36 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/9688 |
Actions (login required)
 |
View Item |
