Kasthuri, B (2015) A clinical study on posterior uveitis. Masters thesis, Madras Medical College, Chennai.
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Abstract
AIM OF THE STUDY: To analyse the posterior uveitis with reference to age and sex incidence, laterality, etiology, chronicity, severity, clinical presentation, sequelae, complication and treatment modalities. Primary Objective: 1. To evaluate the various etiological factors and predisposing factors leading on to posterior uveitis. 2. To assess the clinical presentation in different types of posterior uveitis. 3. To diagnose and start treatment after systematic evaluation. Secondary Objective: 1. To assess visual outcome after treatment of Posterior Uveitis since Posterior uveitis treatment is a challenge to all Ophthalmologists. MATERIALS AND METHODS: The study design was a prospective study of 30 patients with age range of 20-45 years with posterior uveitis, conducted in Regional Institute of Ophthalmology and Ophthalmic Eye Hospital during August 2013 to August 2014 for a period of 12 months. Main criteria for diagnosis: 1. Patients having whitish retinal opacities with indistinct borders (focal/multifocal/diffuse) and vitritis suggestive of retinitis. 2. Patients having round yellowish nodule in the fundus (focal/multifocal/diffuse) suggestive of choroiditis. 3. Patients having yellow or grey white, patchy perivascular cuffing suggestive of active vasculitis. 4. Patients having papillitis with multiple serous detachment suggestive of VKH syndrome. 5. Patients having peripheral tubercles. Exclusion criteria: 1. Post surgical cases, 2. Post trauma cases, 3. Intermediate uveitis (predominant vitritis without active chorioretinal lesion), 4. Predominant anterior segment involvement without active chorioretinal lesion), 5. Patients who lost follow up. CONCLUSION: Posterior uveitis is a serious disease associated with vision threatening complications. Posterior uveitis is more common in the age group of 26-35 years. All cases of posterior uveitis is of chronic duration. All cases of posterior uveitis are severe in nature. Retinochoroiditis is the most common anatomical type comprising more than half of the cases. Posterior uveitis due to infectious causes are common than non infectious causes. Toxoplasma is the most common aetiology detected in posterior uveitis. Toxoplasma is the major infectious aetiology found in posterior uveitis. In non infectious causes Vogt Koyanagi Harada syndrome, vasculitis due to collagen vascular diseases are the common causes. With prompt treatment the disease is controlled in all cases of posterior uveitis. Corticosteroids are the most common drugs used for treatment of posterior uveitis. Immuno modulators are used as a steroid sparing agents in non infectious posterior uveitis and retinal vasculitis. Despite adequate control of the disease the visual outcome is comparatively poor in posterior uveitis. The main reason for poor visual prognosis is the structural damage (chorioretinal atrophy in the macula) caused by the disease followed by complications. In posterior uveitis visual prognosis depends upon the aetiology, area of involvement and complications.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | posterior uveitis : clinical study. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Devi S |
| Date Deposited: | 06 Oct 2018 15:26 |
| Last Modified: | 06 Oct 2018 15:26 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/9687 |
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