Lavanya, D S (2017) A clinical study on Neer Kana Maantham (Acute Naso Pharyngitis) with the evaluation of siddha drug Oma Kudineer. Masters thesis, Government Siddha Medical College, Chennai.
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Abstract
The disease Neer Kana Mantham was taken for the clinical study with Oma kudineer as internal medicine. For the clinical study, 40 patients were selected based on Inclusion and Exclusion criteria. The study is conducted after the drug being screened by the Screening committee and the trial is also approved by the Institutional Ethical Committee (IEC). Animal studies are carried out after obtaining proper permission from the Institutional Animal Ethical Committee (IAEC). Hence the study is safely executed on human volunteer patients and there was no adverse drug reactions noted during the study period. 40 children with Neer kana maantham diagnosed clinically treated in out patient department of Arignar Anna Hospital of Indian Medicine,Chennai-106. They were observed for clinical improvement, laboratory investigation done and treated with trial drug. I like to summarize this study with the following highlights. The efficacies of the trial drug Oma kudineer were studied and observed in this study. Clinical Diagnosis of Neer kana maantham was done on the basis of clinical features described in Bala vagadam(siddha pediatric book). The cost of the trial medicines are low,comparatively economic. These drugs are easily available and the dosage is also convenient. The potency of the trial drug were studied by phytochemical analysis. physico chemical analysis and pharmacological analysis. phytochemical analysis of the trial drug reveals that the presence of Alkaloids, flavonoids, glycosides, carbohydrates, triterpnoids, tannins, phenols& proteins. The physico chemical analysis of the trial drug shows the PH-6, and Ash value - 2.44%, So it shows the safe and effectiveness of the drug. The Pharmacological analysis of the drug reveals that it possesses convincing Anti-inflammatory property. Among the 40% cases treated, 80% cases had shown Good improvement, 15% cases had shown Moderate improvement, 5% had shown Mild improvement. Observation made during the clinical study showed that the trial drug was clinically effective and has no adverse effect. CONCLUSION: Neer kana Maantham is a common disease in children and mainly caused by derangement of kaba kuttram. In this clinical study Oma kudineer was taken as Internal drug respectively. The deranged kabam is settled down by the kaarppu suvai in the trial medicine there by the medicine acts as Ethirurai maruthuvam to cure the disease. Toxicological studies showed no acute toxicity. The drug has got Anti inflammatory activity. The cost of the trial medicines are low. During the clinical study no adverse events were observed. The clinical study confirms the efficacy of the trial drugs by reducing the clinical signs and symptoms like Cough, cold, running nose, Fever, and loss of appetite. Clinical study results found to be Good in 80% cases, Moderate in 15% cases, and Mild in 5% cases. The Clinical trial conducted in selected patients was satisfactory and encouraging. The trial medicine is effective for Neer kana Maantham in children. Through this study, the effectiveness of trial drug is confirmed and re-established by the author and concluded that the TRIAL drug “OMA KUDINEER” is effective in treatment of acute naso pharyngitis (common cold). CONCLUSION CONCLUSION Neer kana Maantham is a common disease in children and mainly caused by derangement of kaba kuttram. In this clinical study Oma kudineer was taken as Internal drug respectively.The deranged kabam is settled down by the kaarppu suvai in the trial medicine there by the medicine acts as Ethirurai maruthuvam to cure the disease.Toxicological studies showed no acute toxicity. The drug has got Anti inflammatory activity .The cost of the trial medicines are low .During the clinical study no adverse events were observed. The clinical study confirms the efficacy of the trial drugs by reducing the clinical signs and symptoms like Cough, cold, running nose ,Fever, and loss of appetite. Clinical study results found to be Good in 80% cases, Moderate in 15% cases, and Mild in 5% cases .The Clinical trial conducted in selected patients was satisfactory and encouraging. The trial medicine is effective for Neer kana Maantham in children. Through this study, the effectiveness of trial drug is confirmed and re-established by the author and concluded that the TRIAL drug “OMA KUDINEER” is effective in treatment of acute naso pharyngitis (common cold).
| Item Type: | Thesis (Masters) |
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| Additional Information: | (Reg.No. 321414104) |
| Uncontrolled Keywords: | Neer Kana Maantham ; Acute Naso Pharyngitis ; siddha drug ; Oma Kudineer ; clinical study. |
| Subjects: | AYUSH > Kuzhanthai Maruthuvam |
| Depositing User: | Kambaraman B |
| Date Deposited: | 24 Sep 2018 02:48 |
| Last Modified: | 24 Sep 2018 02:48 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/9608 |
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