A clinical study on Kalladaippu (Urolithiasis) with the evaluation of siddha drug Karpoora Silasathu Parpam

Sarathkumar, S (2017) A clinical study on Kalladaippu (Urolithiasis) with the evaluation of siddha drug Karpoora Silasathu Parpam. Masters thesis, Government Siddha Medical College, Chennai.

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Abstract

The clinical study on Kalladaippu was carried out in Post graduate department of Pothu Maruthuvam, Government Siddha Medical College, Aringar Anna Hospital, Chennai – 106 during the period of 2015-2017. A total of 40 patients were treated in the Outpatient department. The clinical and pathological assessment was carried out on the basis of Siddha and Modern aspects. All the patients were treated with Karpoora silasathu parpam with Ilaneer 130 mg b.d daily, after food for duration of 48days. males were mostly affected (57.5%). Most of the patients were in the age group between 31-40 years (52.5%). Most of the patients were from Neithal Thinai (82.5%). In this study, most of the cases (35%) were house wives. Most of the patients were affected in Muthuvenirkaalam (37.5%). In Vali, Abanan (100%), Viyanan (100%), Uthanan (30%), and Devadhathan (27.5%) was affected. In Azhal, Saathagam (100%), Ranjagam (22.5%) was affected. In Iyyam, Santhigam (30%) was affected. In Ezhu udal kattugal, Saaram (100%), Seneer (22.5%) and Enbu (30%) was affected. Regarding naadi, (60%) had Vatha Azhal was the most common naadi observed. The Toxicological studies of the trial medicine reveal no toxicity. The Pharmacological studies reveal that, the trial drug has Anti Urolithiatic activity. Bio- statistical analysis of the clinical trial reveals significant p value < 0.05 and ˂ 0.01 and concluded that the treatment is effective and significant. Regarding grading of the result, 17 cases (42.5%) shows good improvement, 19 cases (47.5%) shows moderate improvement, 4 cases (10%) shows poor improvement. CONCLUSION: Kalladaippu is a common disorder of pitha kutram. The dearranged pitham is settled down by the ingredients of trial medicine having astringent taste thereby the medicine acts as ethirurai maruthuvam to cure the disease. Most of the cases noted in muthuvenir kalam and elavenir kalam in my clinical trial. So, people should take all preventive measures during this period and take enough water. Toxicological study shows no acute and sub - acute toxicity. Pharmacological study reveals that the trial medicines possess Anti Urolithiatic activity. During clinical trial, no adverse reactions or complications were observed. The trial medicine Karpoora silasathu parpam showed good results with relieving symptoms in almost 90% patients. Once again Siddha medicine proves itself as a great boon to mankind.

Item Type: Thesis (Masters)
Additional Information: (Reg. No. 321411109)
Uncontrolled Keywords: Kalladaippu ; Urolithiasis ; siddha drug ; Karpoora Silasathu Parpam ; Clinical study.
Subjects: AYUSH > Maruthuvam
Depositing User: Kambaraman B
Date Deposited: 23 Sep 2018 10:43
Last Modified: 23 Sep 2018 11:03
URI: http://repository-tnmgrmu.ac.in/id/eprint/9587

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