Anitha Therese, G (2017) A clinical study on Erigunmam (Peptic Ulcer) with the evaluation of siddha drug Pirandai Vadagam. Masters thesis, Government Siddha Medical College, Chennai.
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Abstract
The clinical study on ERI GUNMAM was carried out in Post Graduate Department of Pothu Maruthuvam, Government Siddha Medical College, Aringar Anna Hospital, Chennai – 106 during the period of 2015-2017. A total of 20 patients were treated in the Outpatient department. The clinical and pathological assessment was carried out on the basis of Siddha and Modern aspects. All the patients were treated with Pirandai Vadagam, 1gm, chewable, b.d daily, after food for duration of 48days. Males were mostly affected (70%). Most of the patients were in the age group between 21-30 years (35%) Most of the patients were from Neithal Thinai (90%). The disease is more common in coolies (45%), so high incidence occurs in men. Most of the patients were affected in Munpanikaalam (75%). The diseases was more common in Pithavatham yakkai cases (65%). In Vali, Abanan (20%), Viyanan (100%), Samanan (100%), Uthanan (100%) Koorman (10%), Kirukaran (45%) and Devadhathan (20%) were affected. In Azhal, Analagam (100%) Ranjagam (25%), Saathagam (100%), Alosagam (10%), were affected. In Iyyam, Kilethegam (100%), Pothagam (55%), Tharpagam (10%) and Santhigam (15%) were affected. In Ezhu udal kattugal, Saaram (100%), Seneer (25%), Oon (10%), and Enbu (15%) were affected. Regarding naadi, Vathapitha naadi (65%) was the most common naadi observed. The Toxicological studies of the trial medicine reveal no toxicity. The Pharmacological studies reveal that, the trial drug has Anti-Ulcer activity. Bio- statistical analysis of the clinical trial reveals significant p value < 0.05 and ˂ 0.01 and concluded that the treatment is effective and significant. Regarding grading of the result, 15 patients (75%) have shown good improvement, 3 patients (15%) have shown fair improvement, 2 patients (10%) have shown poor improvement. CONCLUSION: ERI GUNMAM (Peptic Ulcer) is mainly due to the derangement of Pitha kutram. The trial medicine, Pirandai Vadagam has predominant astringent taste, neutralizes the increased Pitham, thereby it acts on ETHURURAI MARUTHUVAM. The Pirandai Vadagam reveals no toxicity in the preclinical studies and hence proved to be safe for human administration. From the pre clinical pharmacological studies it is evident that, the trial medicine has significant Anti-Ulcer activity and analgesic activity. No contra indication was reported during the course of the treatment. The trial medicine gave maximam relief from the symptoms of ERI GUNMAM. Therefore the author concluded that, the trial medicine PIRANDAI VADAGAM is an effective drug for ERI GUNMAM (Peptic Ulcer).
| Item Type: | Thesis (Masters) |
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| Additional Information: | (Reg. No. 321411102) |
| Uncontrolled Keywords: | Erigunmam ; Peptic Ulcer ; siddha drug ; Pirandai Vadagam ; clinical study. |
| Subjects: | AYUSH > Maruthuvam |
| Depositing User: | Subramani R |
| Date Deposited: | 02 Oct 2018 13:39 |
| Last Modified: | 02 Oct 2018 13:39 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/9566 |
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