Nareshkumar, V (2018) A study of hyponatremia in acute heart failure patients in predicting the acute cardio renal syndrome type 1. Masters thesis, Madurai Medical College, Madurai.
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Abstract
BACKGROUND: Patients with acute heart failure (AHF) are hemodynamicaly unstable. This condition is often accentuated by medication and multiple factors. So that they are sensitive to electrolyte disturbance. Hyponatremia worsen the both cardiac and renal function. AIM OF THE STUDY: The aim of this study was to detect the cause of hyponatremia in AHF patients and to investigate whether hyponatraemia, a surrogate marker of congestion and haemodilution and of neurohormonal activation, could identify patients at risk for WRF. METHODS: We studied the association between hyponatraemia (sodium, 136 mmol/L) and WRF (defined as an increase of .0.3 mg/dL in creatinine above baseline) in AHF patients. They were monitored for six months. RESULTS: Some patients with hyponatraemia on admission was improved with treatment, other are worsened with elevated creatinine after three months of monitoring .With proper electrolyte monitoring and treatment hyponatremia was corrected and creatinine became to acceptale limit on sixth months. The morbidity is decreased with sidoum correction. CONCLUSION: Hyponatraemia predicts the development of WRF in AHF patients and frequently lead to the type I CRS. These data are consistent with the concept that congestion and neurohormonal activation play a pivotal role in the pathophysiology of acute cardio-renal failure.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | acute heart failure ; worsening renal function ; cardio renal syndrome. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 08 Sep 2018 16:08 |
| Last Modified: | 08 Sep 2018 16:08 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/9447 |
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