Chronic Dermatophytosis: A Clinicomycological study

Karthika, S (2006) Chronic Dermatophytosis: A Clinicomycological study. Other thesis, Madras Medical College, Chennai.

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Abstract

Dermatophytosis is a superficial fungal infection of keratinized tissue caused by dermatophytes. They are a group of taxonomically related fungi that utilize keratin as a source of nutrients and colonise keratinized tissues including stratum corneum of epidermis, nail, hair, and horny tissue of animals.1 Though a superficial infection, dermatophytes do evoke inflammatory responses like scaling, vesiculation, pustulation, and sometimes abscess formation, because of their metabolic activities. Thus clinical infection occurs if fungi penetrate the host’s protective barrier. Dermatophytosis is the leading cause of cutaneous fungal infection and accounts for those of the cutaneous fungal infection related medical expenses. Chronic dermatophytosis is a social, economical, psychological burden not only to the patient, but also to those closely associated with them. They act as source of infection constantly spreading with or without their knowledge. Remissions and exacerbations mark the course of the disease and chronic dermatophytosis still remains a challenge to the practicing dermatologist. Multiple factors may affect the incidence of this fungal infection within a population. These include geographic area, climate, immunocompetence of the host, pathogenicity of the agent and availability of the treatment.2 The growing number of immunocompromised patients due to chemotherapy, transplant, HIV, etc has led to increased incidence of dermatophytosis. This study aims to bring out the recent trends in the age, sex, distribution, causative species, factors associated with in chronic dermatophytosis of and more than three years duration. AIM OF STUDY : The aim of this study is to assess the following in cases of chronic dermatophytosis: - Age, sex distribution. - Clinical types of dermatophytosis. - Characteristic features of lesions or morphological features. - Probable factors responsible for chronicity. - Various isolates encountered - Blood group association. CONCLUSION : The 30 – 40 years age group was commonly affected by chronic dermatophytosis. The mean age was 47.8 years. Females were more affected than males. Diabetes mellitus and Bronchial asthma were the commonest associations. Other systemic conditions like hypothyroidism, systemic lupus erythematosus, chronic obstructive pulmonary disease, HIV infection, renal transplantation, hypertension and cutaneus disorder like ichthyosis vulgaris, palmoplantar psoariasis, discoid lupus erythematosus, keratolysis punctata, pemphigus vulgaris on steroids, angioedema and candidiasis were also observed. Tinea corporis was the commonest clinical pattern, especially in waist region in females and back in males. Tinea axillaris and tinea cruris were frequently noted in females and males respectively. Trichophyton rubrum was the commonest isolate with Trichophyton mentagrophytes being the second commonest one. Eosinophilia was observed in 56.6% of the patients. Most of them had diabetes mellitus and bronchial asthma. The frequently associated blood group was ‘O’. This is consistent with the pattern seen in general population.

Item Type: Thesis (Other)
Uncontrolled Keywords: Chronic Dermatophytosis ; Clinico mycological study.
Subjects: MEDICAL > Dermatology Venereology and Leprosy
Depositing User: Subramani R
Date Deposited: 05 Jul 2017 00:47
Last Modified: 01 Mar 2018 16:02
URI: http://repository-tnmgrmu.ac.in/id/eprint/931

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