Study of peritoneal elastic lamina invasion and extramural venous invasion in stage 2 colorectal carcinoma

Shantha Priya, G (2018) Study of peritoneal elastic lamina invasion and extramural venous invasion in stage 2 colorectal carcinoma. Masters thesis, Coimbatore Medical College, Coimbatore.

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Abstract

AIM AND OBJECTIVES: The present study is aimed at evaluating the peritoneal elastic lamina invasion and extramural venous invasion using elastic stain in colorectal cancers and to identify its significance in staging. METHODS: In this study paraffin blocks from 50 colonic carcinoma specimens were stained with H and E stain and Elastic stain. These includes 44 T3 cases and 6 T4 cases. Identification and intactness of elastic lamina was studied in all the cases and recorded. RESULTS: Out of 50 cases studied, 30 cases were identified to have elastic lamina with elastic stain. Among the cases which were staged as T3, 3 cases were found to have peritoneal invasion. Peritoneal invasion was confirmed in all the T4 cases. Venous invasion was found in 3 cases in addition to the 4 cases identified by H and E stain. CONCLUSION: To conclude, elastic stain can be used regularly as surrogate marker to assess peritoneal invasion and lymphovascular invasion for proper staging and better treatment.

Item Type: Thesis (Masters)
Additional Information: Reg.NO.: 201513254
Uncontrolled Keywords: peritoneal elastic lamina invasion ; extramural venous invasion ; stage 2 colorectal carcinoma.
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 19 Aug 2018 03:34
Last Modified: 19 Aug 2018 03:34
URI: http://repository-tnmgrmu.ac.in/id/eprint/9307

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