Bharathi, G (2018) Study of clinical & biochemical factors determining prognosis of patients with acute pyelonephritis. Masters thesis, Tirunelveli Medical College, Tirunelveli.
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Abstract
AIM AND OBJECTIVES: To study the clinical & biochemical factors determining prognosis of patients with acute pyelonephritis. MATERIALS & METHODS: In our study done from june 2016 –june 2017 in Tirunelveli medical college ,50 patients with pyelonephritis with classical clinical features of pyelonephritis ,with radiological evidence were studied.Blood & urine routine,C/S, USG KUB ,CT scan abdomen taken, patients then followed for a period of 2 months & factors determining the prognosis of patients and outcome studied. RESULTS: Out of 50 patients studied 34% belonged to the age group 51-60 .12 were males(24%) ,38 were females(76%).T2DM present in 37 patients (74%),.6 & 7 patients out of 50 presented with altered sensorium & hypotension respectively. Thrombocytopenia seen in 24 patients.(48%).21 patients had poorly controlled diabetic status (42 %) Urine culture showed positive in 22 patients (44%). E.Coli in 16 patients (72 %). Emphysematous pyelonephritis seen in 11 patients (22%)After follow up period of 2 months, 41 patients recovered with antibiotics, 3 needed percutaneous nephrostomy & 6 patients died. 5 out of 6 Patients who died presented with hypotension & altered sensorium. All 6 patients who died presented with thrombocytopenia. All 6 patients who died had HBA1C OF > 7.5 %. CONCLUSION: Acute Pyelonephritis is more common in females,age group 51-60 years. .E.Coli was the predominant organism cultured in urine.Presence of poorly controlled diabetic status,altered sensorium , hypotension, thrombocytopenia, & renal dysfunction associated with poor prognosis. Presence of high risk radiological features associated with poor prognosis.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | clinical & biochemical factors ; determining prognosis ; patients ; acute pyelonephritis. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 10 Aug 2018 01:36 |
| Last Modified: | 11 Aug 2018 16:46 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/9206 |
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