Sarathchandran, B (2018) A comparative study on efficacy of Q switched neodymium-doped yttrium aluminium garnet (Nd:YAG) laser versus 15% trichloroacetic acid (TCA) peel in the treatment of melasma. Masters thesis, Chengalpattu Medical College, Chengalpattu.
|
Text
202000618sarathchandran.pdf Download (3MB) | Preview |
|
|
Text
202000618sarathchandran_abstract.pdf Download (83kB) | Preview |
Abstract
INTRODUCTION: Melasma is an acquired, circumscribed, pigmentary disorder. It is characterized by more or less symmetrically distributed, dark brown macules with well defined geo-graphic borders. It mostly affects the sun exposed areas, particularly forehead, cheeks, temples and upper lips. Melasma is a common disorder of fascial hyperpigmentation that is often resistant to treatment. AIM OF THE STUDY: The aim of the study is to compare the therapeutic efficacy of Q switched Nd-YAG laser versus 15% TCA peel in the treatment of melasma. MATERIALS AND METHODS: 50 patients in the age group more than 18 years were enrolled in the study. Group 1 : Melasma Patients treated with 15% TCA Peel. Group 2 : Melasma patients treated with lowfluence Q switched Nd-yag laser. 1. Number of patients in group 1 = 25. 2. Number of patients in group 2 = 25. TCA peeling was performed every 2 weeks up to 6 sessions, whereas laser treatment was performed every 3 weeks upto 12 weeks. Then followed up for 12 weeks in both groups. MASI score was used before and after treatment for evaluation. RESULTS: In the 15% TCA peel group, mean MASI scores improved from 16.45 to 9.78 and in the laser group from 16.09 to 11.64. MASI shows significantly reduction with 15% TCA than Nd-YAG laser. Worsening of melasma was higher in the group treated with Nd-YAG laser with 16% of patients developing post inflammatory hyperpigmentation & 40% of patients developing rebound hyperpigmentation. CONCLUSION: 15% TCA were better than Q switched Nd:YAG laser for the treatment of melasma. Post inflammatory pigmentation and rebound hyperpigmentation were the serious common side effects associated with Q switched Nd : YAG laser treated group particularly dark skinned people(Fitzpatrick skin type V).
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Q switched neodymium-doped yttrium aluminium garnet (Nd:YAG) laser ; 15% trichloroacetic acid (TCA) ; peel ; treatment ; melasma. |
| Subjects: | MEDICAL > Dermatology Venereology and Leprosy |
| Depositing User: | Subramani R |
| Date Deposited: | 19 Jul 2018 04:02 |
| Last Modified: | 19 Jul 2018 04:02 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/8914 |
Actions (login required)
 |
View Item |
