A study of undifferentiated head and neck cancers and the role of immunohistochemistry.

Sivakumar, - (2008) A study of undifferentiated head and neck cancers and the role of immunohistochemistry. Masters thesis, Madras Medical College, Chennai.


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Cancers of head and neck refers to neoplasm arising from below the skull base to the region of thoracic inlet. They are diverse group of diseases each with distinct epidemiologic, anatomic and pathologic features. They show wide variation in natural history, prognosis and treatment considerations. India is one of the high incidence zones for head and neck cancers. In India, the most common head and neck cancers are those of oral cavity and pharynx. Age adjusted incidence for these sites in Indian population as follows: Males : 10.8 to 38.8/ 1 lakh population, Females : 6 to 15/ 1 lakh population. Some tumor groups challenge routine histopathological classification of malignancies because of the absence of cell morphological differentiation that characterizes their lymphoid, epithelial or mesenchymal origin. This study supports the notion that the immunohistochemical technique has a fundamental role in the investigation and definition of undifferentiated tumor origin, thus determining correct guidance for treatment and possibly improving the prognosis for head and neck oncological patients.

Item Type: Thesis (Masters)
Uncontrolled Keywords: undifferentiated; head and neck cancers; neoplasmas; immunohistochemistry; tumours
Subjects: MEDICAL > Otorhinolaryngology
Depositing User: Devi S
Date Deposited: 04 Jul 2017 04:58
Last Modified: 04 Jul 2017 04:58
URI: http://repository-tnmgrmu.ac.in/id/eprint/878

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