A comparative study of collagen dressing and silver sulphadiazine application in the management of second degree thermal burns

Kalaiselvi, P (2014) A comparative study of collagen dressing and silver sulphadiazine application in the management of second degree thermal burns. Masters thesis, Coimbatore Medical College, Coimbatore.


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BACKGROUND AND OBJECTIVES: In India alone, 60 – 70 lakhs people sustain burns every year. Mortality due to burns is 1.4 lakhs/year. Around 70% of all injuries occur in the age group of 15 – 35 years, the most productive age group. The most logistic approach to burn wound would be a wound cover until such time the body is able to synthesize a cover of its own. In a tropical country like India, closed dressings get easily infected and open dressings get dried up soon. Collagen dressings provide the most physiological interface between the wound surface and the environment. Hence I chose to study the merits and demerits of collagen dressing over the conventional silver sulphadiazine ointment application. METHODS: 70 patients with second degree thermal burns less than 20% TBSA, getting admitted in the General Surgery and Pediatric Surgery Departments of Coimbatore medical college hospital were enrolled for the study from October 2011 to October 2013. Surface area of burns was assessed by “Wallace rule of nine”. The patients were selected based on inclusion and exclusion criteria and randomly assigned to silver sulphadiazine and collagen group. All patients were treated with analgesics, intravenous fluids and antibiotics. Wound washed thoroughly and dried. Both silver sulpha diazine ointment was applied and left open or collagen sheets applied. RESULTS: In this study thermal burns were more common in females between 21-35 years of age. Between the silver sulphadiazine and collagen group, the average pain score (over the scale of 3) on day 1 was 2.19 v/s 1.11. and on day 2 was 1.96 v/s 1.04. The average duration of wound healing was 17.48 and 13.6 days for silver sulphadiazine and collagen groups respectively. Both pain score and wound healing were found to be statistically significant (P value <.01). The incidence of wound infection, need for split skin graft, development of contractures and hypertrophic scars were found to be low in the collagen group. However they were found to be statistically insignificant (P>.05). INTERPRETATION AND CONCLUSION: Collagen application is better than silver sulphadiazine application in the management of burn wounds owing to its better pain relief, rapid wound healing, need for application of dressing only once, early ambulation and early identification of wound infection due to its translucency.

Item Type: Thesis (Masters)
Uncontrolled Keywords: collagen sheets ; collagen application ; silver sulphadiazine application ; burn wound.
Subjects: MEDICAL > General Surgery
Depositing User: Devi S
Date Deposited: 06 Jul 2018 16:25
Last Modified: 07 Jul 2018 17:22
URI: http://repository-tnmgrmu.ac.in/id/eprint/8673

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