Vengatesan, S (2014) A study on lymphoma. Masters thesis, Stanley Medical College, Chennai.
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Abstract
INTRODUCTION: Lymphoma, involves cancers of the lymphatic system. The two main types of lymphoma are hodgkins lymphomas also known as hodgkins disease, and the non hodgkins lymphoma. In hodgkins lymphoma, cells of the lymphatic system multiplying fastly. The cells of HL grow with out any order or without any control. HL can occur almost anywhere in the lymphatic system. HL may occur in lymphnodal site. They may also affect the other parts of the lymphatic system [bone marrow, spleen] HL spread from one group of LN to next group of LN. Non hodgkins lymphoma, accounts,comprises 3 percent of all malignancies. In NHL cells of lymphatic system become abnormal. They undergo division and multiplying without any control. They do not die normally. They spreads to other group of lymph nodes and lymphoid organs in a non contigious manner. The objective of this study is to evaluate clinical presentation, organs involved, incidence among different age groups and incidence of different subtypes of lymphomas. AIM OF THE STUDY: To evaluate 1. the spectrum of clinical presentations in lymphoma patients. 2. organs involved and 3. incidence among specific age groups. 4. the incidence/distribution of different subtypes of lymphomas. MATERIALS AND METHODS: PLACE OF STUDY: Department of General Surgery, Govt. Stanley Medical College and Hospital. DURATION: MAY 2011 TO DEC 2013. STUDY DESIGN: Prospective and retrospective. SAMPLE SIZE: 51. METHODOLOGY: Clinical data, imaging studies and biopsy material of the all the available patients diagnosed as having lymphomas in the institution. CONCLUSION: Total number of patients included in our study is 51. male patients are dominating in numbers Male, female ratio is 2 : 1. In HL, high incidence is found in 2nd and 3rd decades followed by 5th and 6th decades. In NHL, High incidence is found in 5th decade followed by 6th decade. In HL, mixed cellularity is common than other types Lymphocytic depletion type is least common. In NHL, diffuse large B cell lymphoma is common than other types. In both HL and NHL stage lllB is the frequent stage of presentation Lymphadenopathy is the commonest clinical presentation. The most common site of Lymph node involvement is cervical region followed by axillary. GIT is the most frequently involved extranodal site. Stomach is most frequently involved in GIT, followed by small intestine.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | lymphoma ; sub types. |
| Subjects: | MEDICAL > General Surgery |
| Depositing User: | Devi S |
| Date Deposited: | 05 Jul 2018 03:44 |
| Last Modified: | 05 Jul 2018 17:45 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/8643 |
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