Prevalence of mesenteric vascular disease in patients with coronary artery disease

Gautham, K (2014) Prevalence of mesenteric vascular disease in patients with coronary artery disease. Masters thesis, Stanley Medical College, Chennai.


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INTRODUCTION: Atherosclerosis is a global phenomenon affecting the primarily the medium sized arteries irrespective of the vascular bed. Hence the involvement of a vascular site at one site predisposes involvement of another distant site. The prevalence chronic mesenteric ischemia is often underestimated because of its non-specific symptomatology. Patient related and physician related are responsible for the delay in the diagnosis till the stage of bowel infarction when there is high morbidity and mortality. Paucity of studies on the natural course of disease further aggravates the situation. Given the prevalence of coronary artery disease is very high, the same population should also be predisposed for chronic mesenteric ischemia. MATERIALS AND METHODOLOGY: 110 patients, who underwent coronary angiogram for evaluation of suspected coronary artery disease, were subjected to mesenteric angiogram at the same sitting. RESULTS: Out of 110 patients, 7 had normal coronary study. The remaining 103 patients were evaluated for synchronous mesenteric artery involvement. 44 out of 103 (42.7%) had mesenteric involvement out of which 19 had indications for revascularization (p<0.05). There was no difference between the genders. Higher age group (>65 years), diabetic and cases of known peripheral vascular disease were predisposed for mesenteric artery involvement (p<0.05). Superior mesenteric artery was the most common artery involved (72.2%). There was no correlation between the severity of the coronary disease and mesenteric disease. However involvement of left anterior descending artery had positive association with mesenteric artery involvement. CONCLUSION: The prevalence of mesenteric artery disease is common among the coronary artery disease patients. The probability increases in elderly, diabetic and patients with prior history of peripheral vascular disease. Further studies with longer follow-up can help in understanding the natural course of the disease and thereby provide better idea regarding the time of intervention.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Mesenteric vascular disease ; coronary artery disease ; atherosclerosis ; angiogram ; chronic mesenteric ischemia.
Subjects: MEDICAL > General Surgery
Depositing User: Devi S
Date Deposited: 05 Jul 2018 03:43
Last Modified: 05 Jul 2018 16:55

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