Anand, P (2015) Clinical Profile of Hyperthyroidism at Stanley Hospital. Masters thesis, Stanley Medical College, Chennai.
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Abstract
INTRODUCTION: Hyperthyroidism is a condition where thyroid gland produces excessive amount of thyroid hormone. Most common causes are Grave’s disease, toxic multinodular goiter, toxic adenoma, subacute thyroiditis, drugs, secondary hyperthyroidism. Clinical features were palpitation, neck swelling, nervousness, increased appetite & loss of weight, hair loss, heat intolerance, menstrual irregularities, loose stools and easy fatguibility. On examining , patient may have goiter, tremors, eye signs, gynacomastia. Lab investigation will reveal low TSH and high T3 and T4.Thyroid imaging, radioactive iodine uptake study, Thyroid biopsy, Thyroid autoantibodies were other tests to find out the etiology of the disease. Main stay of treatment include antithyroid drugs, radioactive ablation, surgery. Cardiovascular manifestations of hyperthyroidism were tachycardia, atrial fibrillation, increased cardiac output, systolic and diastolic dysfunction, worsening of heart failure, systolic murmur. AIMS AND OBJECTIVES: 1. To study the Clinical Profile of Hyperthyroidism at Stanley Hospital. 2. To study Echocardiographic Findings in these Patients MATERIALS AND METHODS: Place of Study: Department of General Medicine, Endocrinology OPD, Medical OPD, Medical Wards, Stanley Medical College and Hospital, Chennai. Duration: Nov 2013 to Nov 2014. Sample Size: 60. Study Design: Prospective Observational Study. Patient Selection: Any Patient Coming With Symptoms Suggestive of Hyperthyroid to Endocrinology OPD, Medical OPD Medical Wards. Exclusion Criteria: Patients With Known Heart Disease. METHODOLOGY: Patients coming with symptoms suggestive of hyperthyroidism to OPDs from November 2013 to November 2014 are included in the study. Patients will be subjected to symptom analysis, clinical examination, laboratory investigations and Echocardiogram. The final analysis will be made at the end of the study to achieve the forementioned goals. CONCLUSION: • Hyperthyroidism is more common in females of younger age group commonly in third decade of life. • Hyperthyroid patients mostly presents with neck swelling and palpitation and menstrual irregularities forms the significant complaint in my study. • Hyperthyroid has significant effect on cardiac activity. It is a high output state. Causing systolic and diastolic dysfunction, pulmonary hypertension, left ventricle chamber enlargement, heart failure. • Hyperthyroidism-related cardiac changes was largely asymptomatic and reversible after restoration to an euthyroid state. So hyperthyroidism should be considered as the reversible cause in cardiac morbidity. As a non-invasive method, echocardiography can play a vital role in recognizing the cardiac pathology in hyperthyroidism as well as to follow up the response to therapy.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Hyperthyroid ; Echocardiogram ; Grave’s disease. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Punitha K |
| Date Deposited: | 23 Jun 2018 03:20 |
| Last Modified: | 23 Jun 2018 03:20 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/8569 |
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