Study of changes in serum levels of creatine kinase and liver enzymes in organophosphorus poisoning and it’s prognostic significance

Senthil Kumaran, A (2015) Study of changes in serum levels of creatine kinase and liver enzymes in organophosphorus poisoning and it’s prognostic significance. Masters thesis, Chengalpattu Medical College, Chengalpattu.

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Abstract

SUMMARY: 1) In this study which included 110 patients of organophosphorus poisoning brought to Chengalpattu Medical College hospital, 62.72% were males and 37.27% were females. 2) Majority of the patients were in the age group of 20 -40 which constituted 61% of the study population. 3) The severe poisoning group predominantly belonged to older population with a mean age 51.48 years when compared to mild 36 years and moderate 32.02 years. 4) Most common compound consumed was chlorpyrifos (32.72%) followed by methylparathion (19.09%) and dimethoate (17.27%). 5) Most common presenting symptom is abdominal pain (86.36%) and most common presenting sign is miosis (89.09%). 6) Mean CPK, SGOT and SGPT values in case of mild, moderate and severe case of OPC poisoning is 76.5, 38.63 and 45.0 respectively. 7) Mean CPK, SGOT and SGPT values in case of moderate severity in case of OPC poisoning is 249.24, 71.53 and 70.44 respectively. 8) Mean CPK, SGOT and SGPT values in case of severe poisoning is 843.68, 157.54 and 138.32 respectively. 9) Mean CPK, SGOT, SGPT values in case of respiratory failure, intermediate syndrome and death is (815.10, 157.84, 141.57), (857.2, 159.4, 143.40), (940.81, 183.37, 160.37) respectively.

Item Type: Thesis (Masters)
Uncontrolled Keywords: serum levels ; creatine kinase ; liver enzymes ; organophosphorus poisoning ; prognostic significance.
Subjects: MEDICAL > General Medicine
Depositing User: Punitha K
Date Deposited: 16 Jun 2018 01:16
Last Modified: 16 Jun 2018 01:16
URI: http://repository-tnmgrmu.ac.in/id/eprint/8503

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