Short term prognostic importance of hyponatremia in acute ST elevation myocardial infarction

Sadeesh Kumar, V (2006) Short term prognostic importance of hyponatremia in acute ST elevation myocardial infarction. Masters thesis, Thanjavur Medical College, Thanjavur.


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INTRODUCTION: In 1950, the Eighth Edition of the Price Textbook of Medicine, outlining the management of patients with Acute Myocardial Infarction, stated that “taking cases as a whole, it would appear that somewhat more than half survive the acute attack. The first week is particularly dangerous, especially the first two or three days, and prognosis must be very guarded at least three months of complete rest, followed by a period of partial rest is strongly indicated” Retrospectively, this cautionary approach may seem exaggerated, but it must be remembered that until 1912, it was believed that acute myocardial infarction was uniformly fatal. It was James Herrick, a Chicago physician, who first described survival after infarction in an article that appeared in the Journal of the American Medical Association in 1912. AIMS OF THE STUDY: 1. To determine the prevalence and prognostic implications of hyponatremia in the setting of acute ST-elevation myocardial infarction. 2. To validate the accuracy of frequently used prognostic index killip classification. 3. To investigate the relative importance of other prognostic factors cited in the literature. 4. To calculate the statistical associations between such characteristics and short-term prognosis. MATERIALS AND METHODS: This study was conducted in the Thanjavur Medical College Hospital, Thanjavur, during the period of September, 2005 to March, 2006. Study Population: A total of 54 patients admitted to the Intensive Cardiac Care Unit were studied. There were 40 male and 14 female patients, ranging from 35 years to 85 years. Average age of presentation 54.7 years. Criteria For Entry Into The Study: Patients with a diagnosis of Acute Myocardial Infarction (AMI) were entered into the study. A definitive diagnosis of AMI was made if the patients satisfied the following criteria : i) A history of typical chest discomfort, lasting for more than thirty minutes, not relieved by rest or nitrates. ii) Typical ECG changes of AMI (Q waves or ST/T wave changes. in two contiguous leads, or the appearance of new left bundle branch block). Exclusion Criteria: i) Patients with elevated renal parameters. ii) Very late presentation more than 72 hours.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Short term prognostic importance ; hyponatremia ; acute ST elevation myocardial infarction.
Subjects: MEDICAL > General Medicine
Depositing User: Punitha K
Date Deposited: 16 Jun 2018 01:11
Last Modified: 16 Jun 2018 01:11

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