Imayavaramban, C (2016) Comparative evaluation of spinal anaesthesia with levobupivacaine and hyperbaric bupivacaine for caesarean section: A study of 60 cases. Masters thesis, Tirunelveli Medical College, Tirunelveli.
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Abstract
AIM & OBJECTIVES: This study was performed to compare the anesthetic efficacy and safety of two local anesthetic agents : hyperbaric bupivacaine and isobaric levobupivacaine, in patients undergoing elective caesarean section. METHODS AND MATERIALS: Sixty patients, ASA I-II, were randomized to receive an intrathecal injection of hyperbaric bupivacaine or isobaric levobupivacaine. Group B (n = 30) received 2 ml of Hyperbaric bupivacaine 5 mg/ml (10 mg). Group L (n = 30) received 2 ml of isobaric levobupivacaine 5 mg/ml (10 mg). The onset and duration of sensory and motor blockade, recovery parameters, hemodynamic changes and side effects for the two agents were compared. RESULTS: The time of onset of sensory block was faster in Group B(1.46 ± 0.50) when compared with Group L(2.0 ± 0.37). In Group B the time to two segment regression was prolonged (76.16 ± 13.86) when compared with Group L (68.43 ±12.96) and it is statistically significant. Duration of motor blockade was prolonged in Group B(132 ± 7.67) when compared with Group L (99 ± 9.13). Hemodynamic variables were more stable in Group L than Group B. Twelve patients in Group B had adverse effects when compared with seven patients in Group L. CONCLUSION: 0.5% Isobaric Levobupivacaine 10mg for intrathecal injection of caesarean section produces adequate sensory and motor blockade and stable hemodynamic parameters with minimum adverse effects than 0.5% hyperbaric bupivacaine 10mg. We concluded that isobaric Levobupivacaine is a better alternative for caesarean section.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | spinal anaesthesia ; levobupivacaine ; hyperbaric bupivacaine ; caesarean section ; 60 cases. |
| Subjects: | MEDICAL > Anaesthesiology |
| Depositing User: | Punitha K |
| Date Deposited: | 15 Jun 2018 03:31 |
| Last Modified: | 15 Jun 2018 15:24 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/8481 |
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