Comparative quantification study of dynamic MR imaging with CT guided sacroiliac biopsies in the early diagnosis of sacroilitis in spondyloarthropathies

Karthik, - (2016) Comparative quantification study of dynamic MR imaging with CT guided sacroiliac biopsies in the early diagnosis of sacroilitis in spondyloarthropathies. Masters thesis, Madras Medical College, Chennai.

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Abstract

Objective—Sacroiliitis is a hallmark of the spondyloarthropathies (SpA). The degree of inflammation can be quantified by magnetic resonance imaging (MRI). The aim of this study was to further elucidate the pathogenesis of SpA by quantitative cellular analysis of immunostained sacroiliac biopsy specimens and to compare these findings with the degree of enhancement in the sacroiliac joints (SJ) as detected by dynamic MRI. This study shows that T cells and macrophages are the most frequent cells in early and active sacroiliitis in SpA. The correlation of cellularity and MRI enhancement provides further evidence for the role of dynamic MRI to detect early sacroiliitis.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Dynamic MRI ; Spondyloarthropathies ; Sacroilitis ; Inflammatory cells.
Subjects: MEDICAL > Radio Diagnosis
Depositing User: Punitha K
Date Deposited: 03 Jul 2017 11:31
Last Modified: 08 Nov 2018 08:00
URI: http://repository-tnmgrmu.ac.in/id/eprint/846

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