Study on incidence of malignancy in patients undergoing surgery for benign thyroid disease

Elankumar, S (2013) Study on incidence of malignancy in patients undergoing surgery for benign thyroid disease. Masters thesis, Coimbatore Medical College, Coimbatore.


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BACKGROUND: Total thyroidectomy has been suggested by many people at various places for benign thyroid conditions which needs surgical intervention. According to them, one of the important factor in substantiating total thyroidectomy is increased occurrence of incidental carcinoma in resected thyroid specimens. This study was conducted in our hospital to know the incidence of malignancy reported post operatively. METHOD: This was a prospective observational study conducted in Coimbatore Medical College Hospital from the period of September 2011 to November 2012. This study included 109 consecutive patients operated for benign thyroid conditions in our hospital. Patients having proven cytological diagnosis of malignancy were excluded from the study. Specimens of any form of thyroid surgeries( Hemithyroidectomy, subtotal thyroidectomy, Near total thyroidectomy, Isthumectomy) done for benign thyroid conditions were subjected to HPE by serial sectioning technique. HPE reports were documented and analysed. RESULTS: Out of 109 patients (94 females and 15 males in the age range 16-88years), 7 patients were found harbouring malignancy in the resected specimens(6.4%). There were 2 papillary micro carcinoma, 1 papillary carcinoma, 2 follicular carcinoma, 1 minimally invasive follicular carcinoma and 1 lymphoma. Also it was observed that, there was no significant difference in the incidence of malignancy in MNG(6.5%) and SNG(5.4%) patients. CONCLUSION: According to this study, the incidence of thyroid malignancy detected in patients operated for benign conditions was 6.4%. Considering the morbidity associated with total thyroidectomy, it can be concluded that for benign thyroid conditions, conservative thyroid surgery followed by subjecting the specimens for thorough HPE examination and regular follow up of patients is sufficient, so that, positive cases of malignancy can be detected and treated accordingly.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Incidental thyroid carcinoma ; Total thyroidectomy ; Benign thyroid diseases.
Subjects: MEDICAL > General Surgery
Depositing User: Devi S
Date Deposited: 08 Jun 2018 17:52
Last Modified: 08 Jun 2018 17:52

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