Thangapprakasam, P (2013) Study of Clinical, Biochemical and Radiological Correlation in severity of Acute Pancreatitis. Masters thesis, Thanjavur Medical College, Thanjavur.
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Abstract
INTRODUCTION Acute pancreatitis is one of the important causes of acute abdomen. Patients of acute pancreatitis usually get admitted in the surgical emergency units. Generally chronic alcoholism is the important cause of acute pancreatitis in men &biliary tract pathology is the common etiology in women. Various epidemiological studies are concluded that most cases of acute pancreatitis are attributed to chronic alcoholism. The incidence and the prevalence of it are varying in different countries. Lankishet al. reported from twenty studies of acute pancreatitis from various countries of Europe that the biliary tract disease contributes to the majority of cases of acute pancreatitis. The significant variability in data indicates that the accurate measurement of the magnitude of problem is very difficult for the researchers. This is because of the following factors. 1)Lack of standardization in diagnosing acute pancreatitis with the laboratory and clinical background 2)variation in the inclusion and exclusion criteria’s in different studies 3)regarding tools used for the consumption of alcohol 4)confusion between acute and chronic forms. AIMS OF THE STUDY: 1. To analyze the etiologies and the varying clinical presentations of acute pancreatitis. 2. To validate the clinical, biochemical and radiological signs in diagnosing acute pancreatitis. 3. To correlate the severity of acute pancreatitis with the clinical, biochemical and radiological signs. 4. To correlate the prognosis of the disease with the above mentioned parameters. 5. To decide on the surgical intervention in correlation with CT abdomen findings. MATERIALS AND METHODS: PATIENTS: Total of fifty patients include both male and female of adult age group who got admitted in the emergency surgical ward with the symptoms of acute pancreatitis and evaluation confirmed the presence of this serious illness. PLACE OF THE STUDY: Thanjavur Medical College Hospital. PERIOD OF THE STUDY: From August 2010 to September 2012 TYPE OF THE STUDY.: It is a descriptive study. INCLUSION CRITERIA: Patients got admitted in the emergency surgical ward with the symptoms of acute pancreatitis in which the biochemical and radiological evaluation P a g e | 66 confirmed the presence of acute pancreatitis.Patients who had recurrent attacks of acute pancreatitis also included in this study. EXCLUSION CRITERIA: Patients with chronic pancreatitis are excluded from this study. Patients with known co morbid conditions like diabetes mellitus, systemic hypertension, coronary artery disease, chronic obstructive pulmonary disease, chronic kidney disease are excluded from this study. Paediatric age group not included in this study. CONCLUSION: 1. Clinical manifestations like hemodynamic instability, massive ascites and presence of guarding &ridgidity are associated with poor outcome. 2. Serum amylase and lipase has role only in the diagnosis of acute pancreatitis. So the rise of serum amylase and lipase levels cannot be used as a parameter to assess the severity of acute pancreatitis. 3. Ranson’s scoring has an important role in assessing the severity of acute pancreatitis. 4. CT scan plays a very important role in both the diagnosis and assessment of severity of the disease. 5. CT scan is very useful to diagnose other causes mimicking acute pancreatitis 6. Serial CT scanning is useful in predicting the need for surgical intervention.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | acute pancreatitis, clinical, biochemical, radiological correlation, severity. |
| Subjects: | MEDICAL > General Surgery |
| Depositing User: | Devi S |
| Date Deposited: | 07 Jun 2018 02:58 |
| Last Modified: | 27 Mar 2020 03:11 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/8277 |
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