Effect of Hypertension on Nerve Conduction Parameters in Patients Attending Sree Mookambika Institute of Medical Sciences, Kulasekharam

Aswathy, L (2015) Effect of Hypertension on Nerve Conduction Parameters in Patients Attending Sree Mookambika Institute of Medical Sciences, Kulasekharam. Masters thesis, Sree Mookambika Institute of Medical Sciences, Kulasekharam.


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INTRODUCTION: The most important medical and public health issue and the single cause of death worldwide is high blood pressure. The hypertension prevalence is on a rapid increase now a days. Technological innovations are dramatically changing life style of people. Thus according Joint National Committee (JNC – VI) hypertension prevalence is 12.5% in South India. Nerve conduction is a constituent of electrophysiological test. Nerve conduction study measures duration, latency, amplitude and conduction velocity. Age and BMI are important factors that influence hypertension mediated changes in nerve conduction leading to peripheral neuropathy. AIMS & OBJECTIVES: 1.To assess the effect of hypertension on nerve conduction parameters. 2. To study the association of age and body mass index on nerve conduction parameters in hypertensive patients. MATERIALS AND METHODS: A descriptive cross sectional study of 28 normal subjects and 108 hypertensive patients of more than ten years duration with age group between 30-60 years was done and electrophysiological evaluation is done for all the subjects by computerized RMS ALERON 401 EMG/NCV/EP system. Latency (m sec), Duration, amplitude (mv), conduction velocity (mt sec) of 2 motor nerves (tibial nerve and common peroneal nerve) and 2 sensory (superficial peroneal nerve and sural nerve) of both limbs were measured. RESULTS: The results analyzed showed that with increasing BMI, significant blood pressure changes were caused along with increasing age. Hypertension causes significant deterioration of nerve conduction variables at an earlier age. CONCLUSION: Increasing BMI and age caused increased blood pressure and inturn causes slowing of nerve conduction variables in the control subjects.Nerve conduction variables were significantly decreased in the hypertension with increasing BMI and age; and the onset age of these variables has occurred at an younger age.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Nerve conduction study ; hypertension ; latency ; amplitude ; conduction velocity ; duration.
Subjects: MEDICAL > Physiology
Depositing User: Punitha K
Date Deposited: 24 May 2018 17:50
Last Modified: 27 May 2018 11:24
URI: http://repository-tnmgrmu.ac.in/id/eprint/8079

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